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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMNDC1
All Species:
17.27
Human Site:
T117
Identified Species:
31.67
UniProt:
O75940
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75940
NP_005862.1
238
26711
T117
G
Y
G
N
A
E
V
T
P
L
L
N
L
K
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_864410
199
22437
M101
E
D
S
G
N
K
P
M
S
K
K
E
M
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGT7
238
26735
T117
V
Y
G
N
A
E
V
T
P
L
L
N
L
K
P
Rat
Rattus norvegicus
Q4QQU6
238
26765
T117
V
Y
G
N
A
E
V
T
P
L
L
N
L
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512808
309
34597
T188
G
Y
G
N
A
E
V
T
P
L
L
N
L
K
P
Chicken
Gallus gallus
XP_421753
238
26635
T117
G
Y
G
N
A
E
V
T
P
L
F
N
L
K
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZV80
237
26922
M117
G
Y
G
N
A
E
V
M
P
L
H
M
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138001
243
28185
H136
Y
Q
N
R
S
T
T
H
V
N
E
L
R
E
R
Honey Bee
Apis mellifera
XP_393514
235
26699
M117
Y
K
N
T
D
V
T
M
L
S
Q
L
K
S
V
Nematode Worm
Caenorhab. elegans
NP_001022932
239
26048
P110
G
T
K
T
I
V
D
P
A
D
L
Q
L
P
P
Sea Urchin
Strong. purpuratus
XP_782685
238
26660
Q121
Y
E
N
V
E
V
K
Q
L
S
K
L
K
D
I
Poplar Tree
Populus trichocarpa
XP_002328804
287
32224
V133
G
W
G
N
R
E
E
V
D
P
D
N
V
R
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178361
300
33452
E125
E
W
Y
D
A
T
I
E
A
H
T
A
N
G
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.1
N.A.
99.5
99.1
N.A.
75.7
95.8
N.A.
78.1
N.A.
45.6
47.9
33.8
49.5
Protein Similarity:
100
N.A.
N.A.
83.6
N.A.
99.5
99.1
N.A.
76
97.9
N.A.
86.9
N.A.
58.4
64.2
51
67.6
P-Site Identity:
100
N.A.
N.A.
0
N.A.
93.3
93.3
N.A.
100
93.3
N.A.
73.3
N.A.
0
0
26.6
0
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
93.3
93.3
N.A.
100
93.3
N.A.
73.3
N.A.
13.3
0
26.6
0
Percent
Protein Identity:
33.4
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
50.8
N.A.
N.A.
44.3
N.A.
N.A.
P-Site Identity:
40
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
54
0
0
0
16
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
8
0
8
0
8
8
8
0
0
8
0
% D
% Glu:
16
8
0
0
8
54
8
8
0
0
8
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
47
0
54
8
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
8
% I
% Lys:
0
8
8
0
0
8
8
0
0
8
16
0
16
47
8
% K
% Leu:
0
0
0
0
0
0
0
0
16
47
39
24
54
0
0
% L
% Met:
0
0
0
0
0
0
0
24
0
0
0
8
8
0
0
% M
% Asn:
0
0
24
54
8
0
0
0
0
8
0
47
8
0
0
% N
% Pro:
0
0
0
0
0
0
8
8
47
8
0
0
0
8
54
% P
% Gln:
0
8
0
0
0
0
0
8
0
0
8
8
0
0
0
% Q
% Arg:
0
0
0
8
8
0
0
0
0
0
0
0
8
8
8
% R
% Ser:
0
0
8
0
8
0
0
0
8
16
0
0
0
8
0
% S
% Thr:
0
8
0
16
0
16
16
39
0
0
8
0
0
0
0
% T
% Val:
16
0
0
8
0
24
47
8
8
0
0
0
8
0
8
% V
% Trp:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
47
8
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _