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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMNDC1
All Species:
24.85
Human Site:
T222
Identified Species:
45.56
UniProt:
O75940
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75940
NP_005862.1
238
26711
T222
G
I
A
D
K
P
M
T
Q
Y
Q
D
T
S
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_864410
199
22437
Q184
I
A
D
K
P
M
T
Q
Y
Q
D
T
S
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGT7
238
26735
T222
G
I
A
D
K
P
M
T
Q
Y
Q
D
T
S
K
Rat
Rattus norvegicus
Q4QQU6
238
26765
T222
G
I
A
D
K
P
M
T
Q
Y
Q
D
T
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512808
309
34597
T293
G
I
A
D
K
P
M
T
Q
Y
Q
D
T
S
K
Chicken
Gallus gallus
XP_421753
238
26635
T222
G
I
A
D
K
P
M
T
Q
Y
Q
D
T
S
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZV80
237
26922
T221
G
I
A
D
K
P
M
T
Q
Y
N
D
T
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138001
243
28185
A226
G
V
G
T
C
G
T
A
G
K
G
M
T
D
F
Honey Bee
Apis mellifera
XP_393514
235
26699
S218
G
I
G
T
C
G
V
S
G
R
E
M
T
K
F
Nematode Worm
Caenorhab. elegans
NP_001022932
239
26048
S220
E
K
R
G
T
I
V
S
S
R
S
S
Q
F
I
Sea Urchin
Strong. purpuratus
XP_782685
238
26660
G221
G
V
G
T
C
G
V
G
G
Q
P
M
T
K
F
Poplar Tree
Populus trichocarpa
XP_002328804
287
32224
Q270
G
K
G
L
T
E
F
Q
K
R
E
K
H
L
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178361
300
33452
Q282
G
K
G
L
T
D
F
Q
K
R
E
K
H
L
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.1
N.A.
99.5
99.1
N.A.
75.7
95.8
N.A.
78.1
N.A.
45.6
47.9
33.8
49.5
Protein Similarity:
100
N.A.
N.A.
83.6
N.A.
99.5
99.1
N.A.
76
97.9
N.A.
86.9
N.A.
58.4
64.2
51
67.6
P-Site Identity:
100
N.A.
N.A.
0
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
13.3
20
0
13.3
P-Site Similarity:
100
N.A.
N.A.
6.6
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
20
40
13.3
26.6
Percent
Protein Identity:
33.4
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
50.8
N.A.
N.A.
44.3
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
47
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
47
0
8
0
0
0
0
8
47
0
8
0
% D
% Glu:
8
0
0
0
0
8
0
0
0
0
24
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
16
0
0
0
0
0
0
8
24
% F
% Gly:
85
0
39
8
0
24
0
8
24
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
16
% H
% Ile:
8
54
0
0
0
8
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
24
0
8
47
0
0
0
16
8
0
16
0
24
47
% K
% Leu:
0
0
0
16
0
0
0
0
0
0
0
0
0
16
0
% L
% Met:
0
0
0
0
0
8
47
0
0
0
0
24
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
8
47
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
24
47
16
39
0
8
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
31
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
16
8
0
8
8
8
47
0
% S
% Thr:
0
0
0
24
24
0
16
47
0
0
0
8
70
0
0
% T
% Val:
0
16
0
0
0
0
24
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
47
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _