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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMNDC1
All Species:
23.64
Human Site:
Y186
Identified Species:
43.33
UniProt:
O75940
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75940
NP_005862.1
238
26711
Y186
Q
Q
F
N
N
R
A
Y
S
K
N
K
K
G
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_864410
199
22437
S148
Q
F
N
N
R
A
Y
S
K
N
K
K
G
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGT7
238
26735
Y186
Q
Q
F
N
N
R
A
Y
S
K
N
K
K
G
Q
Rat
Rattus norvegicus
Q4QQU6
238
26765
Y186
Q
Q
F
N
N
R
A
Y
S
K
N
K
K
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512808
309
34597
Y257
Q
Q
F
N
N
R
A
Y
S
K
N
K
K
G
Q
Chicken
Gallus gallus
XP_421753
238
26635
Y186
Q
Q
F
N
N
R
A
Y
S
K
N
K
K
G
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZV80
237
26922
Y185
Q
Q
F
N
N
K
A
Y
S
K
N
K
K
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138001
243
28185
L190
E
S
D
K
N
K
W
L
N
F
N
N
K
N
Q
Honey Bee
Apis mellifera
XP_393514
235
26699
W182
R
E
M
E
K
N
K
W
L
A
F
T
N
K
S
Nematode Worm
Caenorhab. elegans
NP_001022932
239
26048
N184
Q
K
F
N
T
K
A
N
A
K
G
L
K
G
L
Sea Urchin
Strong. purpuratus
XP_782685
238
26660
N185
D
Q
K
K
S
W
V
N
F
S
S
K
A
T
K
Poplar Tree
Populus trichocarpa
XP_002328804
287
32224
K234
T
T
K
G
K
T
K
K
V
G
F
F
S
G
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178361
300
33452
K246
T
T
K
A
K
T
K
K
V
G
F
F
T
G
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.1
N.A.
99.5
99.1
N.A.
75.7
95.8
N.A.
78.1
N.A.
45.6
47.9
33.8
49.5
Protein Similarity:
100
N.A.
N.A.
83.6
N.A.
99.5
99.1
N.A.
76
97.9
N.A.
86.9
N.A.
58.4
64.2
51
67.6
P-Site Identity:
100
N.A.
N.A.
20
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
26.6
0
46.6
13.3
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
46.6
20
66.6
33.3
Percent
Protein Identity:
33.4
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
50.8
N.A.
N.A.
44.3
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
54
0
8
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
54
0
0
0
0
0
8
8
24
16
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
16
8
0
8
70
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
24
16
24
24
24
16
8
54
8
62
62
8
8
% K
% Leu:
0
0
0
0
0
0
0
8
8
0
0
8
0
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
62
54
8
0
16
8
8
54
8
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
62
54
0
0
0
0
0
0
0
0
0
0
0
8
54
% Q
% Arg:
8
0
0
0
8
39
0
0
0
0
0
0
0
0
16
% R
% Ser:
0
8
0
0
8
0
0
8
47
8
8
0
8
0
8
% S
% Thr:
16
16
0
0
8
16
0
0
0
0
0
8
8
8
0
% T
% Val:
0
0
0
0
0
0
8
0
16
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
8
8
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _