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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAD17
All Species:
22.73
Human Site:
S281
Identified Species:
38.46
UniProt:
O75943
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75943
NP_002864.1
681
77055
S281
K
E
I
Q
E
E
C
S
I
S
N
I
S
F
N
Chimpanzee
Pan troglodytes
XP_001158997
681
76838
S281
K
E
I
Q
E
E
C
S
I
S
N
I
S
F
N
Rhesus Macaque
Macaca mulatta
XP_001092469
681
77137
S281
K
E
I
Q
E
E
C
S
I
S
N
I
S
F
N
Dog
Lupus familis
XP_535265
680
76892
A278
K
E
I
Q
E
E
C
A
I
A
N
I
S
F
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6NXW6
688
77372
S280
R
N
I
Q
E
E
C
S
V
S
N
I
S
F
N
Rat
Rattus norvegicus
NP_001019949
686
77263
S280
K
N
I
Q
E
E
C
S
V
S
N
I
S
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512393
679
76253
S281
K
E
I
Q
E
E
L
S
V
S
N
I
S
F
N
Chicken
Gallus gallus
NP_998749
694
78107
C288
K
E
I
L
E
E
L
C
I
S
I
I
S
F
K
Frog
Xenopus laevis
NP_001082566
674
75485
V275
K
E
I
Q
E
E
L
V
V
N
N
I
S
F
N
Zebra Danio
Brachydanio rerio
NP_001002661
665
73800
G268
K
D
V
L
Q
E
L
G
I
H
N
I
S
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650382
535
59398
I162
L
Q
E
W
I
N
P
I
D
C
E
V
V
N
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787106
598
66549
S225
N
A
F
Y
R
D
P
S
S
L
H
A
V
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MBA3
599
66800
A226
L
I
D
D
L
P
L
A
N
G
R
H
A
F
E
Baker's Yeast
Sacchar. cerevisiae
P32641
659
75708
L273
N
P
I
N
S
T
L
L
K
K
H
L
K
F
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.2
88.8
N.A.
80.9
79.7
N.A.
72.5
57.9
58.1
50.5
N.A.
27.3
N.A.
N.A.
38.4
Protein Similarity:
100
99.4
98.6
93.9
N.A.
90.2
89.3
N.A.
82.9
72.7
74.8
68.7
N.A.
45.8
N.A.
N.A.
54.6
P-Site Identity:
100
100
100
86.6
N.A.
80
86.6
N.A.
86.6
66.6
73.3
53.3
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
66.6
86.6
73.3
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.9
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
15
0
8
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
43
8
0
8
0
0
0
0
0
% C
% Asp:
0
8
8
8
0
8
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
50
8
0
65
72
0
0
0
0
8
0
0
0
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
86
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
15
8
0
0
0
% H
% Ile:
0
8
72
0
8
0
0
8
43
0
8
72
0
0
8
% I
% Lys:
65
0
0
0
0
0
0
0
8
8
0
0
8
0
8
% K
% Leu:
15
0
0
15
8
0
43
8
0
8
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
15
0
8
0
8
0
0
8
8
65
0
0
8
65
% N
% Pro:
0
8
0
0
0
8
15
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
58
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
50
8
50
0
0
72
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
15
% T
% Val:
0
0
8
0
0
0
0
8
29
0
0
8
15
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _