KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAD17
All Species:
21.82
Human Site:
S421
Identified Species:
36.92
UniProt:
O75943
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75943
NP_002864.1
681
77055
S421
L
D
S
P
R
L
P
S
H
L
S
E
Y
E
R
Chimpanzee
Pan troglodytes
XP_001158997
681
76838
S421
L
D
S
P
Q
L
P
S
H
L
S
E
Y
E
R
Rhesus Macaque
Macaca mulatta
XP_001092469
681
77137
S421
L
D
S
P
R
L
P
S
H
L
S
E
Y
E
R
Dog
Lupus familis
XP_535265
680
76892
S419
L
D
S
P
R
L
P
S
H
L
S
E
H
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6NXW6
688
77372
A420
L
D
S
P
R
L
P
A
H
L
S
E
H
D
R
Rat
Rattus norvegicus
NP_001019949
686
77263
A420
L
A
S
P
R
L
P
A
H
L
S
E
H
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512393
679
76253
S421
F
K
Y
P
R
L
P
S
H
L
T
E
Y
E
R
Chicken
Gallus gallus
NP_998749
694
78107
S433
S
E
F
P
Q
L
P
S
H
L
L
E
H
H
R
Frog
Xenopus laevis
NP_001082566
674
75485
A420
T
D
V
Y
R
L
P
A
H
L
S
E
Y
N
R
Zebra Danio
Brachydanio rerio
NP_001002661
665
73800
P411
T
Q
A
P
K
L
P
P
H
L
T
D
H
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650382
535
59398
V293
S
M
K
T
F
C
S
V
M
Q
Q
N
K
A
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787106
598
66549
T356
L
P
S
S
W
S
S
T
P
S
S
S
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MBA3
599
66800
N357
P
R
P
G
M
E
D
N
Y
H
G
N
E
Q
T
Baker's Yeast
Sacchar. cerevisiae
P32641
659
75708
N411
L
S
E
C
D
N
M
N
G
L
P
E
S
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.2
88.8
N.A.
80.9
79.7
N.A.
72.5
57.9
58.1
50.5
N.A.
27.3
N.A.
N.A.
38.4
Protein Similarity:
100
99.4
98.6
93.9
N.A.
90.2
89.3
N.A.
82.9
72.7
74.8
68.7
N.A.
45.8
N.A.
N.A.
54.6
P-Site Identity:
100
93.3
100
93.3
N.A.
80
73.3
N.A.
73.3
53.3
66.6
40
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
80
73.3
73.3
80
N.A.
0
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.9
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
22
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
43
0
0
8
0
8
0
0
0
0
8
0
15
0
% D
% Glu:
0
8
8
0
0
8
0
0
0
0
0
72
8
36
8
% E
% Phe:
8
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
72
8
0
0
36
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
8
0
8
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
58
0
0
0
0
72
0
0
0
79
8
0
0
0
0
% L
% Met:
0
8
0
0
8
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
15
0
0
0
15
0
15
0
% N
% Pro:
8
8
8
65
0
0
72
8
8
0
8
0
0
0
0
% P
% Gln:
0
8
0
0
15
0
0
0
0
8
8
0
0
15
0
% Q
% Arg:
0
8
0
0
50
0
0
0
0
0
0
0
0
0
72
% R
% Ser:
15
8
50
8
0
8
15
43
0
8
58
8
15
8
8
% S
% Thr:
15
0
0
8
0
0
0
8
0
0
15
0
0
0
15
% T
% Val:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
0
8
0
0
0
36
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _