KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAD17
All Species:
32.42
Human Site:
Y536
Identified Species:
54.87
UniProt:
O75943
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75943
NP_002864.1
681
77055
Y536
W
F
L
I
N
K
K
Y
R
E
N
C
L
A
A
Chimpanzee
Pan troglodytes
XP_001158997
681
76838
Y536
W
F
L
I
N
K
K
Y
R
E
N
C
L
A
A
Rhesus Macaque
Macaca mulatta
XP_001092469
681
77137
Y536
W
F
L
I
Y
K
K
Y
R
E
N
C
L
A
A
Dog
Lupus familis
XP_535265
680
76892
Y534
W
F
I
I
N
K
K
Y
R
E
N
C
L
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6NXW6
688
77372
Y534
W
F
L
I
Q
K
K
Y
R
E
N
C
L
A
A
Rat
Rattus norvegicus
NP_001019949
686
77263
Y535
W
F
L
I
Q
K
K
Y
R
E
N
C
L
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512393
679
76253
Y535
W
F
L
I
N
K
K
Y
R
D
N
C
R
A
A
Chicken
Gallus gallus
NP_998749
694
78107
Y547
W
F
F
I
N
S
K
Y
Q
E
N
C
A
A
A
Frog
Xenopus laevis
NP_001082566
674
75485
H534
W
L
A
I
N
K
K
H
Q
E
N
C
L
A
A
Zebra Danio
Brachydanio rerio
NP_001002661
665
73800
Y525
W
L
H
I
N
K
T
Y
R
E
N
Y
Q
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650382
535
59398
F407
F
N
T
E
P
R
N
F
V
N
F
V
Y
A
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787106
598
66549
E470
L
D
F
Y
T
D
L
E
D
V
V
E
G
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MBA3
599
66800
D471
S
S
Y
L
A
D
A
D
L
L
L
A
D
I
R
Baker's Yeast
Sacchar. cerevisiae
P32641
659
75708
K528
D
K
F
S
D
I
M
K
V
E
N
G
I
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.2
88.8
N.A.
80.9
79.7
N.A.
72.5
57.9
58.1
50.5
N.A.
27.3
N.A.
N.A.
38.4
Protein Similarity:
100
99.4
98.6
93.9
N.A.
90.2
89.3
N.A.
82.9
72.7
74.8
68.7
N.A.
45.8
N.A.
N.A.
54.6
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
86.6
73.3
73.3
60
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
93.3
80
86.6
60
N.A.
26.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.9
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
8
0
0
0
0
8
8
72
72
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
65
0
0
0
% C
% Asp:
8
8
0
0
8
15
0
8
8
8
0
0
8
8
0
% D
% Glu:
0
0
0
8
0
0
0
8
0
72
0
8
0
0
0
% E
% Phe:
8
58
22
0
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
72
0
8
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
8
0
0
0
65
65
8
0
0
0
0
0
0
0
% K
% Leu:
8
15
43
8
0
0
8
0
8
8
8
0
50
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
50
0
8
0
0
8
79
0
0
0
8
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
15
0
0
0
15
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
58
0
0
0
8
0
15
% R
% Ser:
8
8
0
8
0
8
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
8
0
8
0
8
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
15
8
8
8
0
0
8
% V
% Trp:
72
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
8
0
0
65
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _