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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FLOT1 All Species: 16.06
Human Site: S385 Identified Species: 35.33
UniProt: O75955 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75955 NP_005794.1 427 47355 S385 I T L V S S G S G T M G A A K
Chimpanzee Pan troglodytes Q7YR41 427 47395 S385 I T L V S S G S G T M G A A K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848778 427 47321 G385 I T L V S S G G G A M G A A K
Cat Felis silvestris
Mouse Mus musculus O08917 428 47495 S385 I T L V S S G S G T M G A A K
Rat Rattus norvegicus Q9Z1E1 428 47481 S385 I T L V S S G S G T M G A A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DKC0 330 36828 A288 L Q L M K Y Q A I A A N S K I
Zebra Danio Brachydanio rerio Q98TZ8 428 46903 I383 G R T N E I V I L S G D G G R
Tiger Blowfish Takifugu rubipres NP_001092130 424 47436 S382 A H K V T M V S S G D G Q V G
Fruit Fly Dros. melanogaster O61491 426 47117 S385 A K K I T M V S S G T G D I G
Honey Bee Apis mellifera XP_623738 430 47726 K384 A P L S Q A K K I T M V S S G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791741 423 46959 M382 S K A K K I T M V S S G K G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 99 N.A. 98.1 97.9 N.A. N.A. N.A. 20.8 48.1 78.9 63.4 64.1 N.A. 64.8
Protein Similarity: 100 99.7 N.A. 99.3 N.A. 99 99 N.A. N.A. N.A. 38.1 71.2 92.2 85.4 85.3 N.A. 84
P-Site Identity: 100 100 N.A. 86.6 N.A. 100 100 N.A. N.A. N.A. 6.6 0 20 13.3 20 N.A. 6.6
P-Site Similarity: 100 100 N.A. 86.6 N.A. 100 100 N.A. N.A. N.A. 33.3 13.3 26.6 26.6 40 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 0 10 0 0 10 0 10 0 19 10 0 46 46 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 10 10 0 10 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 46 10 46 19 10 73 10 19 28 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 46 0 0 10 0 19 0 10 19 0 0 0 0 10 10 % I
% Lys: 0 19 19 10 19 0 10 10 0 0 0 0 10 10 46 % K
% Leu: 10 0 64 0 0 0 0 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 10 0 19 0 10 0 0 55 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 10 0 10 0 0 0 0 0 10 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 10 0 0 10 46 46 0 55 19 19 10 0 19 10 0 % S
% Thr: 0 46 10 0 19 0 10 0 0 46 10 0 0 0 0 % T
% Val: 0 0 0 55 0 0 28 0 10 0 0 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _