KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK2AP2
All Species:
19.09
Human Site:
S16
Identified Species:
52.5
UniProt:
O75956
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75956
NP_005842.1
126
13101
S16
A
P
S
S
T
P
G
S
S
T
P
G
P
G
T
Chimpanzee
Pan troglodytes
XP_001173121
106
10806
A9
S
Y
K
P
I
A
P
A
P
S
S
T
P
G
S
Rhesus Macaque
Macaca mulatta
XP_001105197
126
13096
S16
A
P
S
S
T
P
G
S
S
T
P
G
P
G
T
Dog
Lupus familis
XP_851807
127
13167
S16
A
P
S
S
T
P
G
S
S
T
P
G
P
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPY4
127
13183
S16
A
P
S
S
T
P
G
S
S
T
P
G
P
G
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507129
107
11485
S10
L
P
S
S
K
T
S
S
A
G
S
V
H
S
P
Chicken
Gallus gallus
NP_001034353
90
9895
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001009898
111
11871
S13
I
A
P
A
P
T
G
S
N
H
T
P
P
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795338
231
24671
S59
G
P
S
S
S
S
S
S
T
Y
S
S
K
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
99.2
98.4
N.A.
97.6
N.A.
N.A.
58.7
51.5
N.A.
69
N.A.
N.A.
N.A.
N.A.
30.7
Protein Similarity:
100
84.1
99.2
98.4
N.A.
98.4
N.A.
N.A.
68.2
60.3
N.A.
77.7
N.A.
N.A.
N.A.
N.A.
39.3
P-Site Identity:
100
13.3
100
100
N.A.
100
N.A.
N.A.
26.6
0
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
40
100
100
N.A.
100
N.A.
N.A.
33.3
0
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
12
0
12
0
12
0
12
12
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
56
0
0
12
0
45
0
67
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% H
% Ile:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
12
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
67
12
12
12
45
12
0
12
0
45
12
67
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
67
67
12
12
23
78
45
12
34
12
0
12
23
% S
% Thr:
0
0
0
0
45
23
0
0
12
45
12
12
0
0
45
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _