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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK2AP2 All Species: 16.67
Human Site: T18 Identified Species: 45.83
UniProt: O75956 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75956 NP_005842.1 126 13101 T18 S S T P G S S T P G P G T P V
Chimpanzee Pan troglodytes XP_001173121 106 10806 S11 K P I A P A P S S T P G S S T
Rhesus Macaque Macaca mulatta XP_001105197 126 13096 T18 S S T P G S S T P G P G T P V
Dog Lupus familis XP_851807 127 13167 T18 S S T P G S S T P G P G T P V
Cat Felis silvestris
Mouse Mus musculus Q9CPY4 127 13183 T18 S S T P G S S T P G P G T P V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507129 107 11485 G12 S S K T S S A G S V H S P S T
Chicken Gallus gallus NP_001034353 90 9895
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001009898 111 11871 H15 P A P T G S N H T P P G S C G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795338 231 24671 Y61 S S S S S S T Y S S K M A A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.3 99.2 98.4 N.A. 97.6 N.A. N.A. 58.7 51.5 N.A. 69 N.A. N.A. N.A. N.A. 30.7
Protein Similarity: 100 84.1 99.2 98.4 N.A. 98.4 N.A. N.A. 68.2 60.3 N.A. 77.7 N.A. N.A. N.A. N.A. 39.3
P-Site Identity: 100 13.3 100 100 N.A. 100 N.A. N.A. 20 0 N.A. 26.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 33.3 100 100 N.A. 100 N.A. N.A. 26.6 0 N.A. 46.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 12 0 12 12 0 0 0 0 0 12 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 56 0 0 12 0 45 0 67 0 0 12 % G
% His: 0 0 0 0 0 0 0 12 0 0 12 0 0 0 0 % H
% Ile: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 0 12 0 0 0 0 0 0 0 12 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % M
% Asn: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % N
% Pro: 12 12 12 45 12 0 12 0 45 12 67 0 12 45 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 67 67 12 12 23 78 45 12 34 12 0 12 23 23 0 % S
% Thr: 0 0 45 23 0 0 12 45 12 12 0 0 45 0 34 % T
% Val: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 45 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _