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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK2AP2
All Species:
16.36
Human Site:
Y74
Identified Species:
45
UniProt:
O75956
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75956
NP_005842.1
126
13101
Y74
A
Q
G
S
Q
S
T
Y
T
D
L
L
S
V
I
Chimpanzee
Pan troglodytes
XP_001173121
106
10806
K63
M
G
Y
V
Q
A
M
K
P
P
G
A
Q
G
S
Rhesus Macaque
Macaca mulatta
XP_001105197
126
13096
Y74
A
Q
G
S
Q
S
T
Y
T
D
L
L
S
V
I
Dog
Lupus familis
XP_851807
127
13167
Y75
A
Q
G
S
Q
S
T
Y
T
D
L
L
S
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPY4
127
13183
Y75
S
Q
G
S
Q
S
T
Y
T
D
L
L
S
V
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507129
107
11485
E64
E
L
L
A
I
I
E
E
L
G
K
E
I
R
P
Chicken
Gallus gallus
NP_001034353
90
9895
E47
E
L
L
A
I
I
E
E
L
G
K
E
I
R
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001009898
111
11871
E67
S
E
L
L
S
V
I
E
E
M
S
R
E
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795338
231
24671
Y179
P
S
A
P
Q
S
K
Y
A
E
L
L
A
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
99.2
98.4
N.A.
97.6
N.A.
N.A.
58.7
51.5
N.A.
69
N.A.
N.A.
N.A.
N.A.
30.7
Protein Similarity:
100
84.1
99.2
98.4
N.A.
98.4
N.A.
N.A.
68.2
60.3
N.A.
77.7
N.A.
N.A.
N.A.
N.A.
39.3
P-Site Identity:
100
6.6
100
100
N.A.
93.3
N.A.
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
N.A.
N.A.
6.6
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
12
23
0
12
0
0
12
0
0
12
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
45
0
0
0
0
0
% D
% Glu:
23
12
0
0
0
0
23
34
12
12
0
23
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
45
0
0
0
0
0
0
23
12
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
23
23
12
0
0
0
0
0
23
12
56
% I
% Lys:
0
0
0
0
0
0
12
12
0
0
23
0
0
0
0
% K
% Leu:
0
23
34
12
0
0
0
0
23
0
56
56
0
0
0
% L
% Met:
12
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
12
0
0
0
0
12
12
0
0
0
0
23
% P
% Gln:
0
45
0
0
67
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
12
0
23
12
% R
% Ser:
23
12
0
45
12
56
0
0
0
0
12
0
45
0
12
% S
% Thr:
0
0
0
0
0
0
45
0
45
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
12
0
0
0
0
0
0
0
56
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _