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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK2AP2
All Species:
17.88
Human Site:
Y92
Identified Species:
49.17
UniProt:
O75956
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75956
NP_005842.1
126
13101
Y92
G
K
E
I
R
P
T
Y
A
G
S
K
S
A
M
Chimpanzee
Pan troglodytes
XP_001173121
106
10806
I81
Y
T
D
L
L
S
V
I
E
E
M
G
K
E
I
Rhesus Macaque
Macaca mulatta
XP_001105197
126
13096
Y92
G
K
E
I
R
P
T
Y
A
G
S
K
S
A
M
Dog
Lupus familis
XP_851807
127
13167
Y93
G
K
E
I
R
P
T
Y
A
G
S
K
S
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPY4
127
13183
Y93
G
K
E
I
R
P
T
Y
A
G
S
K
S
A
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507129
107
11485
R82
G
S
K
S
A
M
E
R
L
K
R
G
I
I
H
Chicken
Gallus gallus
NP_001034353
90
9895
R65
G
S
K
S
A
M
E
R
L
K
R
G
I
I
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001009898
111
11871
E85
A
G
S
K
S
A
M
E
R
L
K
R
G
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795338
231
24671
Y197
G
R
D
I
R
P
T
Y
A
G
S
R
T
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
99.2
98.4
N.A.
97.6
N.A.
N.A.
58.7
51.5
N.A.
69
N.A.
N.A.
N.A.
N.A.
30.7
Protein Similarity:
100
84.1
99.2
98.4
N.A.
98.4
N.A.
N.A.
68.2
60.3
N.A.
77.7
N.A.
N.A.
N.A.
N.A.
39.3
P-Site Identity:
100
0
100
100
N.A.
100
N.A.
N.A.
6.6
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
20
100
100
N.A.
100
N.A.
N.A.
13.3
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
23
12
0
0
56
0
0
0
0
56
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
45
0
0
0
23
12
12
12
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
78
12
0
0
0
0
0
0
0
56
0
34
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% H
% Ile:
0
0
0
56
0
0
0
12
0
0
0
0
23
34
23
% I
% Lys:
0
45
23
12
0
0
0
0
0
23
12
45
12
0
0
% K
% Leu:
0
0
0
12
12
0
0
0
23
12
0
0
0
0
0
% L
% Met:
0
0
0
0
0
23
12
0
0
0
12
0
0
0
45
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
56
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
56
0
0
23
12
0
23
23
0
0
0
% R
% Ser:
0
23
12
23
12
12
0
0
0
0
56
0
45
0
0
% S
% Thr:
0
12
0
0
0
0
56
0
0
0
0
0
12
0
12
% T
% Val:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _