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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIO
All Species:
15.15
Human Site:
S2487
Identified Species:
41.67
UniProt:
O75962
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75962
NP_009049.2
3097
346900
S2487
Q
K
G
G
S
F
W
S
S
I
P
A
S
P
A
Chimpanzee
Pan troglodytes
XP_517637
3314
371651
S2704
G
A
A
S
P
L
N
S
P
L
S
T
S
P
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535785
3062
343915
S2450
Q
K
G
G
S
F
W
S
S
I
P
A
S
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q0KL02
3102
347843
W2490
L
Q
K
G
G
S
F
W
S
S
I
P
A
S
P
Rat
Rattus norvegicus
P97924
2959
336568
C2374
D
E
S
I
K
K
S
C
S
W
H
T
L
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519275
3047
344048
S2437
Q
K
G
G
S
F
W
S
S
I
P
A
S
P
A
Chicken
Gallus gallus
XP_419004
3067
347368
S2457
L
Q
K
G
S
F
W
S
S
I
P
A
S
P
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LUA6
3028
342343
S2416
F
W
S
S
V
P
A
S
P
A
S
R
P
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651960
2263
256958
P1688
F
C
L
V
R
L
N
P
Q
H
D
D
A
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
N.A.
95
N.A.
96.3
60.5
N.A.
93.3
92.5
N.A.
81.6
N.A.
34
N.A.
N.A.
N.A.
Protein Similarity:
100
92.1
N.A.
96.6
N.A.
97.8
74.6
N.A.
95.5
95.1
N.A.
89.1
N.A.
49.3
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
N.A.
100
N.A.
13.3
6.6
N.A.
100
80
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
N.A.
100
N.A.
33.3
13.3
N.A.
100
86.6
N.A.
13.3
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
0
0
12
0
0
12
0
45
23
23
56
% A
% Cys:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
12
12
0
0
0
% D
% Glu:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
23
0
0
0
0
45
12
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
34
56
12
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
0
0
45
12
0
0
0
0
% I
% Lys:
0
34
23
0
12
12
0
0
0
0
0
0
0
0
0
% K
% Leu:
23
0
12
0
0
23
0
0
0
12
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
12
0
12
23
0
45
12
12
56
12
% P
% Gln:
34
23
0
0
0
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
0
0
0
0
0
0
12
0
12
0
% R
% Ser:
0
0
23
23
45
12
12
67
67
12
23
0
56
12
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% T
% Val:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
12
0
0
0
0
45
12
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _