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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIO All Species: 27.58
Human Site: Y2679 Identified Species: 75.83
UniProt: O75962 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75962 NP_009049.2 3097 346900 Y2679 V K L L N P N Y I Y D V P P E
Chimpanzee Pan troglodytes XP_517637 3314 371651 Y2896 V K L L N P N Y I Y D V P P E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535785 3062 343915 Y2642 V K L L N P N Y I Y D V P P E
Cat Felis silvestris
Mouse Mus musculus Q0KL02 3102 347843 Y2682 V K L L N P N Y I Y D V P P E
Rat Rattus norvegicus P97924 2959 336568 R2561 S C T S V I L R W L P P A S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519275 3047 344048 Y2629 V K L L N P N Y I Y D V P P E
Chicken Gallus gallus XP_419004 3067 347368 Y2649 V K L L N P N Y I Y D V P P E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LUA6 3028 342343 Y2609 V K L L N P N Y I Y D V L P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651960 2263 256958 S1875 E S S G N M A S P G K M D G N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92 N.A. 95 N.A. 96.3 60.5 N.A. 93.3 92.5 N.A. 81.6 N.A. 34 N.A. N.A. N.A.
Protein Similarity: 100 92.1 N.A. 96.6 N.A. 97.8 74.6 N.A. 95.5 95.1 N.A. 89.1 N.A. 49.3 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 0 N.A. 100 100 N.A. 93.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 0 N.A. 100 100 N.A. 93.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 12 0 0 0 0 0 12 0 0 % A
% Cys: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 78 0 12 0 0 % D
% Glu: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 78 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 12 0 0 0 0 0 12 0 0 0 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 12 0 0 78 0 0 0 0 0 0 % I
% Lys: 0 78 0 0 0 0 0 0 0 0 12 0 0 0 0 % K
% Leu: 0 0 78 78 0 0 12 0 0 12 0 0 12 0 0 % L
% Met: 0 0 0 0 0 12 0 0 0 0 0 12 0 0 0 % M
% Asn: 0 0 0 0 89 0 78 0 0 0 0 0 0 0 12 % N
% Pro: 0 0 0 0 0 78 0 0 12 0 12 12 67 78 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % R
% Ser: 12 12 12 12 0 0 0 12 0 0 0 0 0 12 0 % S
% Thr: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 12 % T
% Val: 78 0 0 0 12 0 0 0 0 0 0 78 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 78 0 78 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _