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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLRX3
All Species:
47.88
Human Site:
S178
Identified Species:
75.24
UniProt:
O76003
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76003
NP_006532.2
335
37432
S178
K
H
N
I
Q
F
S
S
F
D
I
F
S
D
E
Chimpanzee
Pan troglodytes
XP_508113
335
37439
S178
K
H
N
V
Q
F
S
S
F
D
I
F
S
D
E
Rhesus Macaque
Macaca mulatta
XP_001090479
335
37463
S178
K
H
N
I
Q
F
S
S
F
D
I
F
S
D
E
Dog
Lupus familis
XP_535061
333
37286
S176
K
H
N
I
Q
F
S
S
F
D
I
F
S
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQM9
337
37760
S180
K
H
N
I
Q
F
S
S
F
D
I
F
S
D
E
Rat
Rattus norvegicus
Q9JLZ1
337
37831
S180
K
H
N
I
Q
F
S
S
F
D
I
F
S
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421826
328
36555
S171
K
H
G
I
S
F
S
S
F
D
I
F
S
D
E
Frog
Xenopus laevis
NP_001088850
326
36684
S169
Q
H
K
I
Q
F
S
S
F
D
I
L
S
D
E
Zebra Danio
Brachydanio rerio
Q5XJ54
326
36317
S169
D
H
N
V
Q
Y
S
S
F
D
I
L
S
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392870
223
25333
A93
I
L
D
R
V
D
G
A
N
P
S
A
I
A
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786413
346
38570
T172
E
R
K
I
D
Y
S
T
F
D
I
L
G
D
E
Poplar Tree
Populus trichocarpa
XP_002305803
492
53614
T201
G
E
N
V
K
F
G
T
F
D
I
L
S
D
I
Maize
Zea mays
NP_001149763
499
54030
S203
Q
E
G
V
K
F
G
S
F
D
I
L
T
D
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZPH2
488
53097
S198
E
V
N
V
D
F
G
S
F
D
I
L
S
D
N
Baker's Yeast
Sacchar. cerevisiae
P32642
244
27474
S114
I
L
S
N
A
S
A
S
L
A
N
N
A
K
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98.8
92.8
N.A.
92.2
92.8
N.A.
N.A.
81.4
78.2
71
N.A.
N.A.
32.5
N.A.
56.3
Protein Similarity:
100
99.4
99.4
96.1
N.A.
95.2
95.5
N.A.
N.A.
89.8
86.5
82
N.A.
N.A.
50.7
N.A.
72.5
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
N.A.
86.6
80
73.3
N.A.
N.A.
0
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
N.A.
N.A.
20
N.A.
66.6
Percent
Protein Identity:
32.7
34.8
N.A.
34.6
31.9
N.A.
Protein Similarity:
45.7
47.7
N.A.
47.9
47.4
N.A.
P-Site Identity:
46.6
40
N.A.
53.3
6.6
N.A.
P-Site Similarity:
66.6
66.6
N.A.
66.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
7
7
0
7
0
7
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
14
7
0
0
0
87
0
0
0
87
7
% D
% Glu:
14
14
0
0
0
0
0
0
0
0
0
0
0
0
67
% E
% Phe:
0
0
0
0
0
74
0
0
87
0
0
47
0
0
0
% F
% Gly:
7
0
14
0
0
0
27
0
0
0
0
0
7
0
7
% G
% His:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
0
0
54
0
0
0
0
0
0
87
0
7
0
7
% I
% Lys:
47
0
14
0
14
0
0
0
0
0
0
0
0
7
0
% K
% Leu:
0
14
0
0
0
0
0
0
7
0
0
40
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
60
7
0
0
0
0
7
0
7
7
0
0
14
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
14
0
0
0
54
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
0
7
7
67
80
0
0
7
0
74
0
0
% S
% Thr:
0
0
0
0
0
0
0
14
0
0
0
0
7
0
0
% T
% Val:
0
7
0
34
7
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _