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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSL1D1
All Species:
17.88
Human Site:
S127
Identified Species:
28.1
UniProt:
O76021
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76021
NP_056474.2
490
54973
S127
K
H
G
I
K
T
V
S
Q
I
I
S
L
Q
T
Chimpanzee
Pan troglodytes
XP_001144836
490
54952
S127
K
H
G
I
K
T
V
S
Q
I
I
S
L
Q
T
Rhesus Macaque
Macaca mulatta
XP_001106695
487
54587
S127
K
H
G
I
K
T
I
S
Q
I
I
S
L
Q
T
Dog
Lupus familis
XP_536972
490
54892
S125
K
H
G
I
K
T
I
S
Q
I
I
P
L
R
T
Cat
Felis silvestris
Mouse
Mus musculus
NP_079822
452
50403
H120
Y
K
K
L
L
K
K
H
G
V
N
T
I
S
Q
Rat
Rattus norvegicus
NP_001008876
540
60945
Y143
T
H
I
G
R
H
F
Y
Q
R
K
K
V
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517075
503
55446
T123
S
Q
V
I
P
F
K
T
L
K
T
E
Y
K
P
Chicken
Gallus gallus
P02259
190
20715
Frog
Xenopus laevis
NP_001108267
318
35827
Zebra Danio
Brachydanio rerio
XP_686114
373
42243
T41
Q
A
F
I
K
N
S
T
S
S
Q
K
L
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623930
327
38049
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795794
339
38444
Poplar Tree
Populus trichocarpa
XP_002321931
384
42954
L52
F
F
Y
L
I
L
T
L
K
K
I
P
Q
K
G
Maize
Zea mays
NP_001146382
413
45597
S81
G
A
S
V
C
V
I
S
D
D
R
P
K
S
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191425
446
49952
K114
T
K
D
D
A
M
K
K
I
K
S
E
N
I
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93.6
68.3
N.A.
55.7
37.4
N.A.
39.1
23
36.1
36.1
N.A.
N.A.
24.2
N.A.
27.9
Protein Similarity:
100
99.8
96.5
79.8
N.A.
72.2
52.2
N.A.
58.2
29.3
50
52.4
N.A.
N.A.
38.5
N.A.
44.4
P-Site Identity:
100
100
93.3
80
N.A.
0
13.3
N.A.
6.6
0
0
20
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
26.6
26.6
N.A.
20
0
0
33.3
N.A.
N.A.
0
N.A.
0
Percent
Protein Identity:
24.6
26.1
N.A.
28.5
N.A.
N.A.
Protein Similarity:
42.8
41.8
N.A.
46.1
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
26.6
20
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
7
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
0
0
0
0
7
7
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% E
% Phe:
7
7
7
0
0
7
7
0
0
0
0
0
0
7
0
% F
% Gly:
7
0
27
7
0
0
0
0
7
0
0
0
0
0
7
% G
% His:
0
34
0
0
0
7
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
40
7
0
20
0
7
27
34
0
7
7
0
% I
% Lys:
27
14
7
0
34
7
20
7
7
20
7
14
7
14
0
% K
% Leu:
0
0
0
14
7
7
0
7
7
0
0
0
34
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
7
0
7
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
0
20
0
7
14
% P
% Gln:
7
7
0
0
0
0
0
0
34
0
7
0
7
20
14
% Q
% Arg:
0
0
0
0
7
0
0
0
0
7
7
0
0
7
7
% R
% Ser:
7
0
7
0
0
0
7
34
7
7
7
20
0
14
0
% S
% Thr:
14
0
0
0
0
27
7
14
0
0
7
7
0
0
27
% T
% Val:
0
0
7
7
0
7
14
0
0
7
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
0
0
7
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _