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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RSL1D1 All Species: 15.15
Human Site: S167 Identified Species: 23.81
UniProt: O76021 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76021 NP_056474.2 490 54973 S167 R I R R L L P S L I G R H F Y
Chimpanzee Pan troglodytes XP_001144836 490 54952 S167 R V R R L L P S L I G R H F Y
Rhesus Macaque Macaca mulatta XP_001106695 487 54587 S167 R I R R L L P S L I G R H F Y
Dog Lupus familis XP_536972 490 54892 S165 R I R R L L P S H L G R H F Y
Cat Felis silvestris
Mouse Mus musculus NP_079822 452 50403 I160 V F I T D A R I R R H L P S H
Rat Rattus norvegicus NP_001008876 540 60945 I183 K R G S C S T I R I G H T G M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517075 503 55446 Y163 S H L G K H F Y L R K K D P L
Chicken Gallus gallus P02259 190 20715
Frog Xenopus laevis NP_001108267 318 35827 Q25 V Q A L L A Y Q K N K G N A N
Zebra Danio Brachydanio rerio XP_686114 373 42243 E81 L S H G L R T E S G D V C L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623930 327 38049 I35 H I L Q C V N I I C H L T E E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795794 339 38444 S47 L K V Q L Q I S V W K I T T K
Poplar Tree Populus trichocarpa XP_002321931 384 42954 P92 C L I I D D R P K S G L N K D
Maize Zea mays NP_001146382 413 45597 R121 S T L R T D Y R P Y E S R R R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191425 446 49952 D154 S Y D M F F T D R R I I P L L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93.6 68.3 N.A. 55.7 37.4 N.A. 39.1 23 36.1 36.1 N.A. N.A. 24.2 N.A. 27.9
Protein Similarity: 100 99.8 96.5 79.8 N.A. 72.2 52.2 N.A. 58.2 29.3 50 52.4 N.A. N.A. 38.5 N.A. 44.4
P-Site Identity: 100 93.3 100 86.6 N.A. 0 13.3 N.A. 6.6 0 6.6 6.6 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 6.6 20 N.A. 13.3 0 13.3 13.3 N.A. N.A. 26.6 N.A. 26.6
Percent
Protein Identity: 24.6 26.1 N.A. 28.5 N.A. N.A.
Protein Similarity: 42.8 41.8 N.A. 46.1 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: 20 6.6 N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 14 0 0 0 0 0 0 0 7 0 % A
% Cys: 7 0 0 0 14 0 0 0 0 7 0 0 7 0 0 % C
% Asp: 0 0 7 0 14 14 0 7 0 0 7 0 7 0 7 % D
% Glu: 0 0 0 0 0 0 0 7 0 0 7 0 0 7 7 % E
% Phe: 0 7 0 0 7 7 7 0 0 0 0 0 0 27 7 % F
% Gly: 0 0 7 14 0 0 0 0 0 7 40 7 0 7 0 % G
% His: 7 7 7 0 0 7 0 0 7 0 14 7 27 0 7 % H
% Ile: 0 27 14 7 0 0 7 20 7 27 7 14 0 0 0 % I
% Lys: 7 7 0 0 7 0 0 0 14 0 20 7 0 7 7 % K
% Leu: 14 7 20 7 47 27 0 0 27 7 0 20 0 14 14 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 0 0 0 0 7 0 0 7 0 0 14 0 7 % N
% Pro: 0 0 0 0 0 0 27 7 7 0 0 0 14 7 0 % P
% Gln: 0 7 0 14 0 7 0 7 0 0 0 0 0 0 0 % Q
% Arg: 27 7 27 34 0 7 14 7 20 20 0 27 7 7 7 % R
% Ser: 20 7 0 7 0 7 0 34 7 7 0 7 0 7 0 % S
% Thr: 0 7 0 7 7 0 20 0 0 0 0 0 20 7 0 % T
% Val: 14 7 7 0 0 7 0 0 7 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 14 7 0 7 0 0 0 0 27 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _