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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSL1D1
All Species:
17.27
Human Site:
S247
Identified Species:
27.14
UniProt:
O76021
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76021
NP_056474.2
490
54973
S247
K
L
P
E
K
W
E
S
V
K
L
L
F
V
K
Chimpanzee
Pan troglodytes
XP_001144836
490
54952
S247
K
L
P
E
K
W
E
S
V
K
L
L
F
V
K
Rhesus Macaque
Macaca mulatta
XP_001106695
487
54587
S247
K
L
P
E
K
W
E
S
V
K
L
L
F
V
K
Dog
Lupus familis
XP_536972
490
54892
S245
K
L
P
E
K
W
E
S
V
K
L
L
Y
V
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_079822
452
50403
S233
V
D
N
I
L
A
V
S
E
M
L
S
E
K
L
Rat
Rattus norvegicus
NP_001008876
540
60945
T269
K
R
T
S
K
A
S
T
Q
P
K
V
T
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517075
503
55446
N236
K
L
P
E
K
W
K
N
V
K
M
I
Y
M
K
Chicken
Gallus gallus
P02259
190
20715
Frog
Xenopus laevis
NP_001108267
318
35827
Q98
F
Y
K
K
L
L
A
Q
H
G
I
K
Q
I
S
Zebra Danio
Brachydanio rerio
XP_686114
373
42243
R154
S
D
A
R
I
R
F
R
L
P
S
Q
I
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623930
327
38049
T108
R
R
R
D
Y
E
P
T
I
E
Y
Y
E
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795794
339
38444
P120
M
F
K
K
E
Y
I
P
F
E
A
R
R
K
M
Poplar Tree
Populus trichocarpa
XP_002321931
384
42954
I165
Q
F
F
K
K
K
K
I
P
V
T
L
D
L
K
Maize
Zea mays
NP_001146382
413
45597
I194
R
S
G
T
C
S
G
I
K
V
G
R
L
D
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191425
446
49952
A227
E
I
T
E
N
V
M
A
T
L
N
G
L
V
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93.6
68.3
N.A.
55.7
37.4
N.A.
39.1
23
36.1
36.1
N.A.
N.A.
24.2
N.A.
27.9
Protein Similarity:
100
99.8
96.5
79.8
N.A.
72.2
52.2
N.A.
58.2
29.3
50
52.4
N.A.
N.A.
38.5
N.A.
44.4
P-Site Identity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
60
0
0
6.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
13.3
33.3
N.A.
100
0
20
13.3
N.A.
N.A.
33.3
N.A.
26.6
Percent
Protein Identity:
24.6
26.1
N.A.
28.5
N.A.
N.A.
Protein Similarity:
42.8
41.8
N.A.
46.1
N.A.
N.A.
P-Site Identity:
20
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
46.6
6.6
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
14
7
7
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
0
7
0
0
0
0
0
0
0
0
7
7
0
% D
% Glu:
7
0
0
40
7
7
27
0
7
14
0
0
14
7
14
% E
% Phe:
7
14
7
0
0
0
7
0
7
0
0
0
20
0
0
% F
% Gly:
0
0
7
0
0
0
7
0
0
7
7
7
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
7
0
7
14
7
0
7
7
7
7
0
% I
% Lys:
40
0
14
20
47
7
14
0
7
34
7
7
0
14
47
% K
% Leu:
0
34
0
0
14
7
0
0
7
7
34
34
14
7
14
% L
% Met:
7
0
0
0
0
0
7
0
0
7
7
0
0
7
14
% M
% Asn:
0
0
7
0
7
0
0
7
0
0
7
0
0
7
0
% N
% Pro:
0
0
34
0
0
0
7
7
7
14
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
7
7
0
0
7
7
0
0
% Q
% Arg:
14
14
7
7
0
7
0
7
0
0
0
14
7
0
0
% R
% Ser:
7
7
0
7
0
7
7
34
0
0
7
7
0
0
7
% S
% Thr:
0
0
14
7
0
0
0
14
7
0
7
0
7
0
0
% T
% Val:
7
0
0
0
0
7
7
0
34
14
0
7
0
34
0
% V
% Trp:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
7
7
0
0
0
0
7
7
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _