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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSL1D1
All Species:
10.3
Human Site:
S325
Identified Species:
16.19
UniProt:
O76021
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76021
NP_056474.2
490
54973
S325
K
D
D
V
A
P
E
S
G
D
T
T
V
K
K
Chimpanzee
Pan troglodytes
XP_001144836
490
54952
S325
K
D
D
V
A
P
D
S
G
D
T
T
V
K
K
Rhesus Macaque
Macaca mulatta
XP_001106695
487
54587
S324
K
D
D
V
A
P
E
S
G
D
T
T
V
K
K
Dog
Lupus familis
XP_536972
490
54892
I327
E
E
D
A
D
P
K
I
S
D
A
V
A
K
D
Cat
Felis silvestris
Mouse
Mus musculus
NP_079822
452
50403
N292
L
K
K
R
K
R
E
N
A
K
L
K
K
E
S
Rat
Rattus norvegicus
NP_001008876
540
60945
G348
Q
E
T
R
G
Q
K
G
G
Q
S
F
E
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517075
503
55446
S308
P
F
F
G
A
S
L
S
R
G
K
K
H
R
G
Chicken
Gallus gallus
P02259
190
20715
S30
S
A
S
H
P
T
Y
S
E
M
I
A
A
A
I
Frog
Xenopus laevis
NP_001108267
318
35827
E157
H
F
Y
K
A
K
R
E
P
Q
S
V
N
L
K
Zebra Danio
Brachydanio rerio
XP_686114
373
42243
A213
V
A
H
S
E
M
T
A
D
Q
I
V
E
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623930
327
38049
L167
A
G
H
L
S
H
L
L
G
K
E
F
Y
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795794
339
38444
A179
E
I
T
E
T
I
D
A
A
Y
L
I
L
T
H
Poplar Tree
Populus trichocarpa
XP_002321931
384
42954
D224
A
A
I
N
G
I
A
D
I
V
P
R
K
W
G
Maize
Zea mays
NP_001146382
413
45597
K253
V
V
P
E
L
G
M
K
I
E
V
P
E
I
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191425
446
49952
E286
V
Q
E
E
K
E
G
E
V
E
E
V
V
A
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93.6
68.3
N.A.
55.7
37.4
N.A.
39.1
23
36.1
36.1
N.A.
N.A.
24.2
N.A.
27.9
Protein Similarity:
100
99.8
96.5
79.8
N.A.
72.2
52.2
N.A.
58.2
29.3
50
52.4
N.A.
N.A.
38.5
N.A.
44.4
P-Site Identity:
100
93.3
100
26.6
N.A.
6.6
13.3
N.A.
13.3
6.6
13.3
0
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
100
100
100
46.6
N.A.
20
46.6
N.A.
20
6.6
20
6.6
N.A.
N.A.
33.3
N.A.
26.6
Percent
Protein Identity:
24.6
26.1
N.A.
28.5
N.A.
N.A.
Protein Similarity:
42.8
41.8
N.A.
46.1
N.A.
N.A.
P-Site Identity:
0
0
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
0
6.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
20
0
7
34
0
7
14
14
0
7
7
14
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
27
0
7
0
14
7
7
27
0
0
0
0
7
% D
% Glu:
14
14
7
20
7
7
20
14
7
14
14
0
20
7
0
% E
% Phe:
0
14
7
0
0
0
0
0
0
0
0
14
0
0
0
% F
% Gly:
0
7
0
7
14
7
7
7
34
7
0
0
0
0
14
% G
% His:
7
0
14
7
0
7
0
0
0
0
0
0
7
0
7
% H
% Ile:
0
7
7
0
0
14
0
7
14
0
14
7
0
7
14
% I
% Lys:
20
7
7
7
14
7
14
7
0
14
7
14
14
40
34
% K
% Leu:
7
0
0
7
7
0
14
7
0
0
14
0
7
7
0
% L
% Met:
0
0
0
0
0
7
7
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
7
0
0
0
0
7
7
0
% N
% Pro:
7
0
7
0
7
27
0
0
7
0
7
7
0
0
0
% P
% Gln:
7
7
0
0
0
7
0
0
0
20
0
0
0
0
0
% Q
% Arg:
0
0
0
14
0
7
7
0
7
0
0
7
0
7
7
% R
% Ser:
7
0
7
7
7
7
0
34
7
0
14
0
0
0
7
% S
% Thr:
0
0
14
0
7
7
7
0
0
0
20
20
0
7
0
% T
% Val:
20
7
0
20
0
0
0
0
7
7
7
27
27
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
7
0
0
0
7
0
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _