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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RSL1D1 All Species: 12.12
Human Site: T312 Identified Species: 19.05
UniProt: O76021 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76021 NP_056474.2 490 54973 T312 K R Q Q A R K T A S V L S K D
Chimpanzee Pan troglodytes XP_001144836 490 54952 T312 K R Q Q A R K T A S V L S K D
Rhesus Macaque Macaca mulatta XP_001106695 487 54587 S311 K K R Q A R K S A S V L S K D
Dog Lupus familis XP_536972 490 54892 A314 L E K Q G K K A A S A P K E E
Cat Felis silvestris
Mouse Mus musculus NP_079822 452 50403 S279 E N A V S L R S L R K Q E L K
Rat Rattus norvegicus NP_001008876 540 60945 P335 A Q G E E G G P G P H C G Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517075 503 55446 T295 E P G E V Q E T L L V T L P F
Chicken Gallus gallus P02259 190 20715 V17 A P A K P K R V K A S R R S A
Frog Xenopus laevis NP_001108267 318 35827 P144 A R I R R F L P S L L G K H F
Zebra Danio Brachydanio rerio XP_686114 373 42243 P200 L T V S T K G P C C M A R V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623930 327 38049 L154 V G S Y D Y F L V D G K I A G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795794 339 38444 K166 P V T V N V E K A D L K K E I
Poplar Tree Populus trichocarpa XP_002321931 384 42954 I211 V S M S R E E I A K N V M A A
Maize Zea mays NP_001146382 413 45597 A240 L K A V D S V A L P I Y Q V V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191425 446 49952 G273 K L K I D A F G S G K S V V Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93.6 68.3 N.A. 55.7 37.4 N.A. 39.1 23 36.1 36.1 N.A. N.A. 24.2 N.A. 27.9
Protein Similarity: 100 99.8 96.5 79.8 N.A. 72.2 52.2 N.A. 58.2 29.3 50 52.4 N.A. N.A. 38.5 N.A. 44.4
P-Site Identity: 100 100 80 26.6 N.A. 0 0 N.A. 13.3 0 6.6 0 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 100 53.3 N.A. 26.6 26.6 N.A. 40 26.6 26.6 13.3 N.A. N.A. 0 N.A. 26.6
Percent
Protein Identity: 24.6 26.1 N.A. 28.5 N.A. N.A.
Protein Similarity: 42.8 41.8 N.A. 46.1 N.A. N.A.
P-Site Identity: 6.6 0 N.A. 6.6 N.A. N.A.
P-Site Similarity: 20 13.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 20 0 20 7 0 14 40 7 7 7 0 14 20 % A
% Cys: 0 0 0 0 0 0 0 0 7 7 0 7 0 0 0 % C
% Asp: 0 0 0 0 20 0 0 0 0 14 0 0 0 0 20 % D
% Glu: 14 7 0 14 7 7 20 0 0 0 0 0 7 14 14 % E
% Phe: 0 0 0 0 0 7 14 0 0 0 0 0 0 0 14 % F
% Gly: 0 7 14 0 7 7 14 7 7 7 7 7 7 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % H
% Ile: 0 0 7 7 0 0 0 7 0 0 7 0 7 0 7 % I
% Lys: 27 14 14 7 0 20 27 7 7 7 14 14 20 20 7 % K
% Leu: 20 7 0 0 0 7 7 7 20 14 14 20 7 7 0 % L
% Met: 0 0 7 0 0 0 0 0 0 0 7 0 7 0 0 % M
% Asn: 0 7 0 0 7 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 7 14 0 0 7 0 0 20 0 14 0 7 0 7 0 % P
% Gln: 0 7 14 27 0 7 0 0 0 0 0 7 7 7 7 % Q
% Arg: 0 20 7 7 14 20 14 0 0 7 0 7 14 0 0 % R
% Ser: 0 7 7 14 7 7 0 14 14 27 7 7 20 7 0 % S
% Thr: 0 7 7 0 7 0 0 20 0 0 0 7 0 0 0 % T
% Val: 14 7 7 20 7 7 7 7 7 0 27 7 7 20 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 7 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _