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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RSL1D1 All Species: 10.3
Human Site: T388 Identified Species: 16.19
UniProt: O76021 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76021 NP_056474.2 490 54973 T388 V E I Q K H A T G K K S P A K
Chimpanzee Pan troglodytes XP_001144836 490 54952 T388 V E I Q K H A T G K K S P A K
Rhesus Macaque Macaca mulatta XP_001106695 487 54587 T387 V E I Q K H A T G K K S P T K
Dog Lupus familis XP_536972 490 54892 A388 I E V Q N H A A G K K S Q K K
Cat Felis silvestris
Mouse Mus musculus NP_079822 452 50403 P352 E E C E E A I P Q L V P I G E
Rat Rattus norvegicus NP_001008876 540 60945 K432 R Q S R R R S K G C W P V L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517075 503 55446 K380 T P K V T P K K P E A S S S A
Chicken Gallus gallus P02259 190 20715 A90 K Q T K G V G A S G S F R L A
Frog Xenopus laevis NP_001108267 318 35827 E217 A V A K V L A E K L P M K W K
Zebra Danio Brachydanio rerio XP_686114 373 42243 L273 E A Q K K A R L T K G A Q K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623930 327 38049 N227 K K K E I L E N I L A T C R Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795794 339 38444 S239 V R T E K S V S L P I Y T S L
Poplar Tree Populus trichocarpa XP_002321931 384 42954 R284 E E K A K E G R V G K K K G R
Maize Zea mays NP_001146382 413 45597 M313 Q V E D D V A M Q E E V Q V E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191425 446 49952 K346 I V E S E E K K M K K R K K E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93.6 68.3 N.A. 55.7 37.4 N.A. 39.1 23 36.1 36.1 N.A. N.A. 24.2 N.A. 27.9
Protein Similarity: 100 99.8 96.5 79.8 N.A. 72.2 52.2 N.A. 58.2 29.3 50 52.4 N.A. N.A. 38.5 N.A. 44.4
P-Site Identity: 100 100 93.3 60 N.A. 6.6 6.6 N.A. 6.6 0 13.3 13.3 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 93.3 73.3 N.A. 26.6 40 N.A. 20 13.3 20 33.3 N.A. N.A. 20 N.A. 33.3
Percent
Protein Identity: 24.6 26.1 N.A. 28.5 N.A. N.A.
Protein Similarity: 42.8 41.8 N.A. 46.1 N.A. N.A.
P-Site Identity: 20 6.6 N.A. 13.3 N.A. N.A.
P-Site Similarity: 26.6 26.6 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 7 0 14 40 14 0 0 14 7 0 14 14 % A
% Cys: 0 0 7 0 0 0 0 0 0 7 0 0 7 0 0 % C
% Asp: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 20 40 14 20 14 14 7 7 0 14 7 0 0 0 20 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 7 0 14 0 34 14 7 0 0 14 0 % G
% His: 0 0 0 0 0 27 0 0 0 0 0 0 0 0 0 % H
% Ile: 14 0 20 0 7 0 7 0 7 0 7 0 7 0 0 % I
% Lys: 14 7 20 20 40 0 14 20 7 40 40 7 20 20 34 % K
% Leu: 0 0 0 0 0 14 0 7 7 20 0 0 0 14 7 % L
% Met: 0 0 0 0 0 0 0 7 7 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 7 0 0 0 7 0 7 7 7 7 14 20 0 0 % P
% Gln: 7 14 7 27 0 0 0 0 14 0 0 0 20 0 0 % Q
% Arg: 7 7 0 7 7 7 7 7 0 0 0 7 7 7 20 % R
% Ser: 0 0 7 7 0 7 7 7 7 0 7 34 7 14 0 % S
% Thr: 7 0 14 0 7 0 0 20 7 0 0 7 7 7 0 % T
% Val: 27 20 7 7 7 14 7 0 7 0 7 7 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _