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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RSL1D1 All Species: 10.61
Human Site: T454 Identified Species: 16.67
UniProt: O76021 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76021 NP_056474.2 490 54973 T454 G K K D A R Q T P K K P E A K
Chimpanzee Pan troglodytes XP_001144836 490 54952 T454 G K K D A R Q T P K K P E A K
Rhesus Macaque Macaca mulatta XP_001106695 487 54587 P452 K K D A R Q T P K K P G A R F
Dog Lupus familis XP_536972 490 54892 K454 G K K D P R Q K T K K P G A R
Cat Felis silvestris
Mouse Mus musculus NP_079822 452 50403 Q417 K K Q K K D V Q E F R K P E A
Rat Rattus norvegicus NP_001008876 540 60945 Y504 R T N Y N D R Y D E I R R H W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517075 503 55446 T461 R K A T P K K T P R K P E A R
Chicken Gallus gallus P02259 190 20715 K155 A S P K K A K K P K T V K A K
Frog Xenopus laevis NP_001108267 318 35827 S283 A K S K S P D S G V T S D A T
Zebra Danio Brachydanio rerio XP_686114 373 42243 A338 K K V P K P A A G N S V K K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623930 327 38049 T292 H N V S G E L T T A P G I A T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795794 339 38444 E304 K T L K R T K E E T V T P A K
Poplar Tree Populus trichocarpa XP_002321931 384 42954 V349 D G V K Q K K V K N E D G I K
Maize Zea mays NP_001146382 413 45597 M378 E Q R K K K S M N G D G E V G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191425 446 49952 K411 K V K P D V V K L E K S K D G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93.6 68.3 N.A. 55.7 37.4 N.A. 39.1 23 36.1 36.1 N.A. N.A. 24.2 N.A. 27.9
Protein Similarity: 100 99.8 96.5 79.8 N.A. 72.2 52.2 N.A. 58.2 29.3 50 52.4 N.A. N.A. 38.5 N.A. 44.4
P-Site Identity: 100 100 13.3 66.6 N.A. 6.6 0 N.A. 46.6 26.6 13.3 6.6 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 100 100 20 73.3 N.A. 20 13.3 N.A. 73.3 40 33.3 13.3 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: 24.6 26.1 N.A. 28.5 N.A. N.A.
Protein Similarity: 42.8 41.8 N.A. 46.1 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 13.3 N.A. N.A.
P-Site Similarity: 26.6 26.6 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 7 7 14 7 7 7 0 7 0 0 7 54 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 20 7 14 7 0 7 0 7 7 7 7 0 % D
% Glu: 7 0 0 0 0 7 0 7 14 14 7 0 27 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % F
% Gly: 20 7 0 0 7 0 0 0 14 7 0 20 14 0 14 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 7 0 7 7 0 % I
% Lys: 34 54 27 40 27 20 27 20 14 34 34 7 20 7 34 % K
% Leu: 0 0 7 0 0 0 7 0 7 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 0 7 0 0 0 7 14 0 0 0 0 0 % N
% Pro: 0 0 7 14 14 14 0 7 27 0 14 27 14 0 0 % P
% Gln: 0 7 7 0 7 7 20 7 0 0 0 0 0 0 0 % Q
% Arg: 14 0 7 0 14 20 7 0 0 7 7 7 7 7 14 % R
% Ser: 0 7 7 7 7 0 7 7 0 0 7 14 0 0 7 % S
% Thr: 0 14 0 7 0 7 7 27 14 7 14 7 0 0 14 % T
% Val: 0 7 20 0 0 7 14 7 0 7 7 14 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _