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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSL1D1
All Species:
15.15
Human Site:
Y142
Identified Species:
23.81
UniProt:
O76021
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76021
NP_056474.2
490
54973
Y142
L
K
K
E
Y
K
S
Y
E
A
K
L
R
L
L
Chimpanzee
Pan troglodytes
XP_001144836
490
54952
Y142
L
K
K
E
Y
K
S
Y
E
A
K
L
R
L
L
Rhesus Macaque
Macaca mulatta
XP_001106695
487
54587
Y142
L
K
K
E
Y
K
S
Y
E
A
K
L
R
L
L
Dog
Lupus familis
XP_536972
490
54892
Y140
L
K
K
E
Y
K
A
Y
E
A
K
L
R
L
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_079822
452
50403
K135
I
I
P
F
K
T
L
K
T
E
Y
K
A
Y
E
Rat
Rattus norvegicus
NP_001008876
540
60945
N158
S
V
N
L
L
A
K
N
L
S
K
E
I
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517075
503
55446
L138
F
E
A
K
R
R
L
L
N
S
F
S
V
F
L
Chicken
Gallus gallus
P02259
190
20715
Frog
Xenopus laevis
NP_001108267
318
35827
Zebra Danio
Brachydanio rerio
XP_686114
373
42243
L56
N
D
G
Q
P
I
S
L
L
F
T
L
W
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623930
327
38049
D10
M
L
D
D
K
V
K
D
D
N
N
E
D
I
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795794
339
38444
I22
K
E
A
A
T
A
L
I
A
Y
H
K
T
K
K
Poplar Tree
Populus trichocarpa
XP_002321931
384
42954
K67
V
S
R
I
N
A
H
K
I
P
L
P
N
S
L
Maize
Zea mays
NP_001146382
413
45597
L96
S
P
S
A
S
D
L
L
H
A
S
K
S
L
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191425
446
49952
S129
I
T
K
V
I
K
L
S
K
L
K
S
D
Y
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93.6
68.3
N.A.
55.7
37.4
N.A.
39.1
23
36.1
36.1
N.A.
N.A.
24.2
N.A.
27.9
Protein Similarity:
100
99.8
96.5
79.8
N.A.
72.2
52.2
N.A.
58.2
29.3
50
52.4
N.A.
N.A.
38.5
N.A.
44.4
P-Site Identity:
100
100
100
93.3
N.A.
0
6.6
N.A.
6.6
0
0
13.3
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
6.6
13.3
N.A.
33.3
0
0
26.6
N.A.
N.A.
26.6
N.A.
6.6
Percent
Protein Identity:
24.6
26.1
N.A.
28.5
N.A.
N.A.
Protein Similarity:
42.8
41.8
N.A.
46.1
N.A.
N.A.
P-Site Identity:
6.6
13.3
N.A.
20
N.A.
N.A.
P-Site Similarity:
20
13.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
14
0
20
7
0
7
34
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
7
0
7
0
7
7
0
0
0
14
0
7
% D
% Glu:
0
14
0
27
0
0
0
0
27
7
0
14
0
0
7
% E
% Phe:
7
0
0
7
0
0
0
0
0
7
7
0
0
7
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
7
0
7
0
0
0
7
% H
% Ile:
14
7
0
7
7
7
0
7
7
0
0
0
7
7
7
% I
% Lys:
7
27
34
7
14
34
14
14
7
0
40
20
0
14
14
% K
% Leu:
27
7
0
7
7
0
34
20
14
7
7
34
0
34
40
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
7
0
0
7
7
7
7
0
7
7
0
% N
% Pro:
0
7
7
0
7
0
0
0
0
7
0
7
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
7
7
0
0
0
0
0
0
27
0
7
% R
% Ser:
14
7
7
0
7
0
27
7
0
14
7
14
7
7
0
% S
% Thr:
0
7
0
0
7
7
0
0
7
0
7
0
7
0
0
% T
% Val:
7
7
0
7
0
7
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
27
0
0
27
0
7
7
0
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _