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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RSL1D1 All Species: 15.15
Human Site: Y142 Identified Species: 23.81
UniProt: O76021 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76021 NP_056474.2 490 54973 Y142 L K K E Y K S Y E A K L R L L
Chimpanzee Pan troglodytes XP_001144836 490 54952 Y142 L K K E Y K S Y E A K L R L L
Rhesus Macaque Macaca mulatta XP_001106695 487 54587 Y142 L K K E Y K S Y E A K L R L L
Dog Lupus familis XP_536972 490 54892 Y140 L K K E Y K A Y E A K L R L L
Cat Felis silvestris
Mouse Mus musculus NP_079822 452 50403 K135 I I P F K T L K T E Y K A Y E
Rat Rattus norvegicus NP_001008876 540 60945 N158 S V N L L A K N L S K E I N R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517075 503 55446 L138 F E A K R R L L N S F S V F L
Chicken Gallus gallus P02259 190 20715
Frog Xenopus laevis NP_001108267 318 35827
Zebra Danio Brachydanio rerio XP_686114 373 42243 L56 N D G Q P I S L L F T L W K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623930 327 38049 D10 M L D D K V K D D N N E D I D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795794 339 38444 I22 K E A A T A L I A Y H K T K K
Poplar Tree Populus trichocarpa XP_002321931 384 42954 K67 V S R I N A H K I P L P N S L
Maize Zea mays NP_001146382 413 45597 L96 S P S A S D L L H A S K S L H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191425 446 49952 S129 I T K V I K L S K L K S D Y K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93.6 68.3 N.A. 55.7 37.4 N.A. 39.1 23 36.1 36.1 N.A. N.A. 24.2 N.A. 27.9
Protein Similarity: 100 99.8 96.5 79.8 N.A. 72.2 52.2 N.A. 58.2 29.3 50 52.4 N.A. N.A. 38.5 N.A. 44.4
P-Site Identity: 100 100 100 93.3 N.A. 0 6.6 N.A. 6.6 0 0 13.3 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 6.6 13.3 N.A. 33.3 0 0 26.6 N.A. N.A. 26.6 N.A. 6.6
Percent
Protein Identity: 24.6 26.1 N.A. 28.5 N.A. N.A.
Protein Similarity: 42.8 41.8 N.A. 46.1 N.A. N.A.
P-Site Identity: 6.6 13.3 N.A. 20 N.A. N.A.
P-Site Similarity: 20 13.3 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 14 0 20 7 0 7 34 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 7 0 7 0 7 7 0 0 0 14 0 7 % D
% Glu: 0 14 0 27 0 0 0 0 27 7 0 14 0 0 7 % E
% Phe: 7 0 0 7 0 0 0 0 0 7 7 0 0 7 0 % F
% Gly: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 7 0 7 0 7 0 0 0 7 % H
% Ile: 14 7 0 7 7 7 0 7 7 0 0 0 7 7 7 % I
% Lys: 7 27 34 7 14 34 14 14 7 0 40 20 0 14 14 % K
% Leu: 27 7 0 7 7 0 34 20 14 7 7 34 0 34 40 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 7 0 7 0 0 7 7 7 7 0 7 7 0 % N
% Pro: 0 7 7 0 7 0 0 0 0 7 0 7 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 0 7 7 0 0 0 0 0 0 27 0 7 % R
% Ser: 14 7 7 0 7 0 27 7 0 14 7 14 7 7 0 % S
% Thr: 0 7 0 0 7 7 0 0 7 0 7 0 7 0 0 % T
% Val: 7 7 0 7 0 7 0 0 0 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 0 27 0 0 27 0 7 7 0 0 14 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _