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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WFS1
All Species:
8.18
Human Site:
Y480
Identified Species:
20
UniProt:
O76024
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76024
NP_001139325.1
890
100306
Y480
S
M
P
L
N
W
P
Y
L
K
V
L
G
Q
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092811
890
100277
Y480
S
M
P
L
N
W
P
Y
L
K
V
L
G
Q
T
Dog
Lupus familis
XP_539234
888
99170
H479
T
L
P
C
G
W
Q
H
L
K
L
L
G
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
P56695
890
100560
F482
T
V
P
V
D
W
R
F
L
K
V
L
G
Q
T
Rat
Rattus norvegicus
NP_114011
890
100514
F482
T
M
P
V
D
W
P
F
L
K
A
L
G
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420803
874
100245
F465
I
L
P
G
N
F
G
F
L
K
F
L
G
K
T
Frog
Xenopus laevis
NP_001089845
863
98792
Y454
L
L
P
I
S
L
P
Y
V
K
I
L
S
K
T
Zebra Danio
Brachydanio rerio
XP_684510
895
100567
V477
N
R
L
L
G
G
W
V
G
R
I
I
G
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651079
853
96770
F427
V
V
S
T
R
W
R
F
L
D
L
R
V
P
T
Honey Bee
Apis mellifera
XP_625196
864
98275
F452
V
V
A
Q
G
W
R
F
L
D
I
R
V
P
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98
83.4
N.A.
87
86.5
N.A.
N.A.
78.1
73.8
54.7
N.A.
21.9
21.9
N.A.
N.A.
Protein Similarity:
100
N.A.
98.9
90.7
N.A.
93
92.5
N.A.
N.A.
88.4
84.8
71.9
N.A.
43
43.5
N.A.
N.A.
P-Site Identity:
100
N.A.
100
53.3
N.A.
60
66.6
N.A.
N.A.
46.6
40
13.3
N.A.
20
20
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
80
N.A.
93.3
93.3
N.A.
N.A.
73.3
80
40
N.A.
40
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
20
0
0
0
0
20
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
50
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
10
30
10
10
0
10
0
0
0
70
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
0
0
0
0
30
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
70
0
0
0
20
0
% K
% Leu:
10
30
10
30
0
10
0
0
80
0
20
70
0
0
0
% L
% Met:
0
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
70
0
0
0
40
0
0
0
0
0
0
20
0
% P
% Gln:
0
0
0
10
0
0
10
0
0
0
0
0
0
50
0
% Q
% Arg:
0
10
0
0
10
0
30
0
0
10
0
20
0
0
0
% R
% Ser:
20
0
10
0
10
0
0
0
0
0
0
0
10
0
0
% S
% Thr:
30
0
0
10
0
0
0
0
0
0
0
0
0
0
90
% T
% Val:
20
30
0
20
0
0
0
10
10
0
30
0
20
0
0
% V
% Trp:
0
0
0
0
0
70
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _