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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLPX
All Species:
31.82
Human Site:
S220
Identified Species:
70
UniProt:
O76031
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76031
NP_006651.2
633
69224
S220
A
E
V
E
K
Q
T
S
L
T
P
R
E
L
E
Chimpanzee
Pan troglodytes
XP_001174382
633
69287
S220
A
E
V
E
K
Q
T
S
L
T
P
R
E
L
E
Rhesus Macaque
Macaca mulatta
XP_001108768
633
69173
S220
A
E
V
E
K
Q
T
S
L
T
P
R
E
L
E
Dog
Lupus familis
XP_852508
633
69269
S220
A
E
V
E
K
Q
T
S
L
T
P
R
E
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHS4
634
69295
S221
A
E
A
E
K
Q
T
S
L
T
P
R
E
L
E
Rat
Rattus norvegicus
Q5U2U0
633
69189
S220
A
E
V
E
K
Q
T
S
L
T
P
R
E
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025723
630
69053
S217
A
E
V
E
K
Q
T
S
L
T
P
R
E
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001004581
610
66412
S210
V
E
V
E
K
Q
A
S
L
T
P
R
E
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650843
673
71260
I249
A
G
G
G
L
D
G
I
P
R
P
D
L
L
H
Honey Bee
Apis mellifera
XP_394615
586
64407
T209
P
H
L
L
H
I
S
T
I
G
N
S
L
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797563
615
66512
G217
K
N
G
G
D
V
E
G
K
G
Q
S
G
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.3
98.4
N.A.
95.7
96.2
N.A.
N.A.
91.7
N.A.
81.1
N.A.
53.4
58.4
N.A.
61.3
Protein Similarity:
100
100
99.8
99
N.A.
97.7
98.4
N.A.
N.A.
95.8
N.A.
87.6
N.A.
65
70.3
N.A.
73.9
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
100
N.A.
80
N.A.
20
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
100
N.A.
80
N.A.
20
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
73
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
10
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
73
0
73
0
0
10
0
0
0
0
0
73
0
64
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
19
19
0
0
10
10
0
19
0
0
10
10
0
% G
% His:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
10
0
10
10
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
73
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
10
10
10
0
0
0
73
0
0
0
19
82
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
10
0
0
10
0
% N
% Pro:
10
0
0
0
0
0
0
0
10
0
82
0
0
0
0
% P
% Gln:
0
0
0
0
0
73
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
73
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
73
0
0
0
19
0
0
0
% S
% Thr:
0
0
0
0
0
0
64
10
0
73
0
0
0
0
0
% T
% Val:
10
0
64
0
0
10
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _