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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLPX All Species: 31.21
Human Site: S463 Identified Species: 68.67
UniProt: O76031 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76031 NP_006651.2 633 69224 S463 A A D L A N R S G E S N T H Q
Chimpanzee Pan troglodytes XP_001174382 633 69287 S463 A A D L A N R S G E S N T H Q
Rhesus Macaque Macaca mulatta XP_001108768 633 69173 S463 A A D L A N R S G E S N T H Q
Dog Lupus familis XP_852508 633 69269 S463 A A D L A N R S G E S N T H Q
Cat Felis silvestris
Mouse Mus musculus Q9JHS4 634 69295 S464 A R D L A N R S G E S N T H Q
Rat Rattus norvegicus Q5U2U0 633 69189 S463 A A D L A N R S G E S N T H Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025723 630 69053 S460 A A D L A N I S G E P N T H E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001004581 610 66412 T439 A A D L A N T T G G E V D A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650843 673 71260 P502 A A Q S A A S P M D N D Q E E
Honey Bee Apis mellifera XP_394615 586 64407 A428 A A N L A D V A N M S P S T E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797563 615 66512 S455 I A D Q T N Q S E G S S A K E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.3 98.4 N.A. 95.7 96.2 N.A. N.A. 91.7 N.A. 81.1 N.A. 53.4 58.4 N.A. 61.3
Protein Similarity: 100 100 99.8 99 N.A. 97.7 98.4 N.A. N.A. 95.8 N.A. 87.6 N.A. 65 70.3 N.A. 73.9
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. N.A. 80 N.A. 46.6 N.A. 20 33.3 N.A. 33.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. N.A. 86.6 N.A. 53.3 N.A. 46.6 66.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 91 91 0 0 91 10 0 10 0 0 0 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 82 0 0 10 0 0 0 10 0 10 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 64 10 0 0 10 37 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 73 19 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 64 0 % H
% Ile: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 82 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 82 0 0 10 0 10 64 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 10 10 0 0 0 % P
% Gln: 0 0 10 10 0 0 10 0 0 0 0 0 10 0 55 % Q
% Arg: 0 10 0 0 0 0 55 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 0 0 10 73 0 0 73 10 10 0 0 % S
% Thr: 0 0 0 0 10 0 10 10 0 0 0 0 64 10 0 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _