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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC14L2 All Species: 40.3
Human Site: S52 Identified Species: 88.67
UniProt: O76054 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76054 NP_036561.1 403 46145 S52 R S F D L Q K S E A M L R K H
Chimpanzee Pan troglodytes XP_515071 403 46057 S52 R S F D L Q K S E A M L R K H
Rhesus Macaque Macaca mulatta XP_001109597 400 46061 S52 R N F D L Q K S E A M L R K Y
Dog Lupus familis XP_534734 506 57636 S155 R N F D L Q K S E A M L R K H
Cat Felis silvestris
Mouse Mus musculus Q99J08 403 46282 S52 R S F D L Q K S E A M L R K H
Rat Rattus norvegicus Q99MS0 403 46148 S52 R S F D L Q K S E A M L R K H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517853 400 45921 S52 R N F D L Q K S E A M I R K Y
Chicken Gallus gallus XP_415298 410 46556 S52 R S F D L P K S E A M L R K H
Frog Xenopus laevis NP_001091144 410 47382 S54 R S F N L Q K S E N M L R K N
Zebra Danio Brachydanio rerio NP_001093463 395 45282 S52 R N F N L Q K S E A M L R K H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q03606 719 81064 A294 R D F D V A K A K D M V H A S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 76.9 73.1 N.A. 93.3 93.8 N.A. 72.6 74.6 72.9 66 N.A. N.A. N.A. 20.1 N.A.
Protein Similarity: 100 100 88.8 77.6 N.A. 97.7 97.7 N.A. 85.8 89 87 83.1 N.A. N.A. N.A. 34 N.A.
P-Site Identity: 100 100 86.6 93.3 N.A. 100 100 N.A. 80 93.3 80 86.6 N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 93.3 100 N.A. N.A. N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 10 0 82 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 82 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 91 0 0 0 0 0 0 % E
% Phe: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 64 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 100 0 10 0 0 0 0 91 0 % K
% Leu: 0 0 0 0 91 0 0 0 0 0 0 82 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % M
% Asn: 0 37 0 19 0 0 0 0 0 10 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 82 0 0 0 0 0 0 0 0 0 % Q
% Arg: 100 0 0 0 0 0 0 0 0 0 0 0 91 0 0 % R
% Ser: 0 55 0 0 0 0 0 91 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _