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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STC2 All Species: 23.94
Human Site: S39 Identified Species: 52.67
UniProt: O76061 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76061 NP_003705.1 302 33249 S39 E G P Q D R S S Q Q K G R L S
Chimpanzee Pan troglodytes XP_001154684 302 33258 S39 E G P Q D R S S Q Q K G R L S
Rhesus Macaque Macaca mulatta XP_001097342 302 33297 S39 E G P Q D R S S Q Q K G R L S
Dog Lupus familis XP_546230 302 33221 S39 E G P Q D R G S Q Q K G R L S
Cat Felis silvestris
Mouse Mus musculus O88452 296 32583 S39 E G P Q D R S S Q Q K G R L S
Rat Rattus norvegicus Q9R0K8 296 32603 S39 E G P Q D R G S Q Q K G R L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505259 169 19601
Chicken Gallus gallus XP_414534 455 48038 P190 E G Q P E R T P Q Q K G R L S
Frog Xenopus laevis NP_001088352 251 27805 V12 T A L L L L P V L L I S V S A
Zebra Danio Brachydanio rerio NP_001014827 283 31314 S36 S H P E K P A S Q K G R L S L
Tiger Blowfish Takifugu rubipres NP_001072057 283 31543 G39 E K P A I Q K G R L S L Q N T
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.6 91 N.A. 85.7 84.1 N.A. 42.3 47 29.7 56.9 56.2 N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 99 93.7 N.A. 90.7 89.7 N.A. 50 52.9 49 69.8 68.5 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 N.A. 0 66.6 0 20 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 93.3 N.A. 0 80 6.6 40 40 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 0 10 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 55 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 73 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 64 0 0 0 0 19 10 0 0 10 64 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 10 0 0 10 0 10 0 0 10 64 0 0 0 0 % K
% Leu: 0 0 10 10 10 10 0 0 10 19 0 10 10 64 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 73 10 0 10 10 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 55 0 10 0 0 73 64 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 64 0 0 10 0 0 10 64 0 0 % R
% Ser: 10 0 0 0 0 0 37 64 0 0 10 10 0 19 64 % S
% Thr: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _