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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM7SF2
All Species:
36.06
Human Site:
S309
Identified Species:
56.67
UniProt:
O76062
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76062
NP_003264.2
418
46406
S309
Y
I
F
R
G
A
N
S
Q
K
N
T
F
R
K
Chimpanzee
Pan troglodytes
XP_514234
615
70705
S506
V
I
F
R
G
A
N
S
Q
K
N
A
F
R
K
Rhesus Macaque
Macaca mulatta
XP_001118188
516
56907
S407
Y
I
F
R
G
A
N
S
Q
K
N
T
F
R
K
Dog
Lupus familis
XP_533236
418
46607
S309
Y
I
F
R
G
A
N
S
Q
K
N
T
F
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q71KT5
418
46474
S309
Y
I
F
R
G
A
N
S
Q
K
N
T
F
R
K
Rat
Rattus norvegicus
O08984
620
70706
S511
V
I
F
R
C
A
N
S
Q
K
N
A
F
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514233
614
70236
S505
I
I
F
R
C
A
N
S
Q
K
N
A
F
R
R
Chicken
Gallus gallus
P23913
637
73480
S499
Y
I
F
R
S
A
N
S
Q
K
N
N
F
R
R
Frog
Xenopus laevis
Q7ZXH1
473
54804
G364
D
L
F
R
R
T
N
G
N
C
K
I
W
G
K
Zebra Danio
Brachydanio rerio
Q7SXF1
478
55171
G369
D
L
F
R
R
T
E
G
N
C
S
I
W
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MLV1
741
83167
A631
L
V
K
R
F
S
C
A
Y
K
Y
K
Y
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786536
578
65964
S469
F
I
F
R
M
S
N
S
E
K
N
A
Y
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDR4
369
41895
Q264
V
F
R
G
A
N
K
Q
K
H
I
F
K
K
N
Baker's Yeast
Sacchar. cerevisiae
P32462
438
50597
H329
F
L
G
F
H
I
F
H
S
A
N
K
Q
K
S
Red Bread Mold
Neurospora crassa
P38670
490
54704
S349
S
I
F
R
L
S
N
S
Q
K
N
N
F
R
T
Conservation
Percent
Protein Identity:
100
40.9
78
91.3
N.A.
86.1
41.4
N.A.
41
39
35.5
33
N.A.
20.9
N.A.
N.A.
39.1
Protein Similarity:
100
52.2
79.2
94.5
N.A.
91.3
51.7
N.A.
51.1
48.9
50.9
50.8
N.A.
33
N.A.
N.A.
48.2
P-Site Identity:
100
86.6
100
100
N.A.
100
80
N.A.
73.3
80
26.6
20
N.A.
20
N.A.
N.A.
53.3
P-Site Similarity:
100
86.6
100
100
N.A.
100
80
N.A.
80
86.6
40
40
N.A.
46.6
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
41.5
39.8
Protein Similarity:
N.A.
N.A.
N.A.
54.5
58.4
53.8
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
54
0
7
0
7
0
27
0
0
0
% A
% Cys:
0
0
0
0
14
0
7
0
0
14
0
0
0
0
0
% C
% Asp:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% E
% Phe:
14
7
80
7
7
0
7
0
0
0
0
7
60
0
0
% F
% Gly:
0
0
7
7
34
0
0
14
0
0
0
0
0
14
0
% G
% His:
0
0
0
0
7
0
0
7
0
7
0
0
0
0
0
% H
% Ile:
7
67
0
0
0
7
0
0
0
0
7
14
0
0
0
% I
% Lys:
0
0
7
0
0
0
7
0
7
74
7
14
7
14
54
% K
% Leu:
7
20
0
0
7
0
0
0
0
0
0
0
0
0
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
74
0
14
0
74
14
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
60
0
0
0
7
0
7
% Q
% Arg:
0
0
7
87
14
0
0
0
0
0
0
0
0
74
14
% R
% Ser:
7
0
0
0
7
20
0
67
7
0
7
0
0
0
7
% S
% Thr:
0
0
0
0
0
14
0
0
0
0
0
27
0
0
7
% T
% Val:
20
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% W
% Tyr:
34
0
0
0
0
0
0
0
7
0
7
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _