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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM7SF2
All Species:
28.18
Human Site:
Y171
Identified Species:
44.29
UniProt:
O76062
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76062
NP_003264.2
418
46406
Y171
G
N
S
G
N
P
I
Y
D
F
F
L
G
R
E
Chimpanzee
Pan troglodytes
XP_514234
615
70705
D367
S
S
G
N
A
V
Y
D
F
F
I
G
R
E
L
Rhesus Macaque
Macaca mulatta
XP_001118188
516
56907
Y269
G
I
S
G
N
P
I
Y
D
F
F
L
G
R
E
Dog
Lupus familis
XP_533236
418
46607
Y171
G
N
S
G
N
P
I
Y
D
F
F
L
G
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q71KT5
418
46474
Y171
G
N
S
G
N
S
M
Y
D
F
F
L
G
R
E
Rat
Rattus norvegicus
O08984
620
70706
D372
S
S
G
N
A
V
Y
D
F
F
I
G
R
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514233
614
70236
D366
K
S
G
N
V
I
Y
D
F
F
I
G
R
E
L
Chicken
Gallus gallus
P23913
637
73480
Y359
G
N
S
G
Y
L
V
Y
D
F
F
T
G
H
E
Frog
Xenopus laevis
Q7ZXH1
473
54804
D216
F
T
G
N
F
F
Y
D
Y
M
M
G
I
E
F
Zebra Danio
Brachydanio rerio
Q7SXF1
478
55171
N221
F
T
G
N
M
F
Y
N
Y
M
M
G
I
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MLV1
741
83167
V472
G
R
T
G
S
F
V
V
D
F
A
L
G
R
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786536
578
65964
Y330
G
N
S
G
N
F
F
Y
D
F
F
M
G
H
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDR4
369
41895
A151
L
K
F
F
F
V
R
A
G
M
M
G
W
L
L
Baker's Yeast
Sacchar. cerevisiae
P32462
438
50597
Y195
G
N
S
G
N
I
I
Y
D
W
F
I
G
R
E
Red Bread Mold
Neurospora crassa
P38670
490
54704
Y206
G
V
T
G
S
L
I
Y
D
F
Y
I
G
R
E
Conservation
Percent
Protein Identity:
100
40.9
78
91.3
N.A.
86.1
41.4
N.A.
41
39
35.5
33
N.A.
20.9
N.A.
N.A.
39.1
Protein Similarity:
100
52.2
79.2
94.5
N.A.
91.3
51.7
N.A.
51.1
48.9
50.9
50.8
N.A.
33
N.A.
N.A.
48.2
P-Site Identity:
100
6.6
93.3
100
N.A.
86.6
6.6
N.A.
6.6
66.6
0
0
N.A.
46.6
N.A.
N.A.
73.3
P-Site Similarity:
100
13.3
93.3
100
N.A.
93.3
13.3
N.A.
13.3
73.3
0
0
N.A.
73.3
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
41.5
39.8
Protein Similarity:
N.A.
N.A.
N.A.
54.5
58.4
53.8
P-Site Identity:
N.A.
N.A.
N.A.
0
80
60
P-Site Similarity:
N.A.
N.A.
N.A.
0
93.3
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
14
0
0
7
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
27
60
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
54
% E
% Phe:
14
0
7
7
14
27
7
0
20
74
47
0
0
0
14
% F
% Gly:
60
0
34
60
0
0
0
0
7
0
0
40
60
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% H
% Ile:
0
7
0
0
0
14
34
0
0
0
20
14
14
0
0
% I
% Lys:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
0
0
0
14
0
0
0
0
0
34
0
7
27
% L
% Met:
0
0
0
0
7
0
7
0
0
20
20
7
0
0
0
% M
% Asn:
0
40
0
34
40
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
7
0
0
0
0
7
0
0
0
0
0
20
47
0
% R
% Ser:
14
20
47
0
14
7
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
14
14
0
0
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
7
0
0
7
20
14
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% W
% Tyr:
0
0
0
0
7
0
34
54
14
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _