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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM7SF2
All Species:
44.55
Human Site:
Y398
Identified Species:
70
UniProt:
O76062
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76062
NP_003264.2
418
46406
Y398
E
R
Q
C
L
Q
K
Y
G
L
A
W
Q
E
Y
Chimpanzee
Pan troglodytes
XP_514234
615
70705
Y595
E
Y
H
C
K
K
K
Y
G
V
A
W
E
K
Y
Rhesus Macaque
Macaca mulatta
XP_001118188
516
56907
Y496
E
R
Q
C
L
Q
K
Y
G
L
A
W
Q
E
Y
Dog
Lupus familis
XP_533236
418
46607
Y398
E
Q
Q
C
L
Q
K
Y
G
L
A
W
H
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q71KT5
418
46474
Y398
E
Q
Q
C
L
Q
K
Y
G
R
A
W
Q
E
Y
Rat
Rattus norvegicus
O08984
620
70706
Y600
E
H
Q
C
R
R
K
Y
G
L
A
W
E
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514233
614
70236
Y594
E
N
H
C
K
K
K
Y
G
L
A
W
E
K
Y
Chicken
Gallus gallus
P23913
637
73480
Y588
E
H
H
C
K
K
K
Y
G
L
A
W
E
R
Y
Frog
Xenopus laevis
Q7ZXH1
473
54804
Y453
E
H
R
C
S
S
K
Y
G
K
D
W
K
L
Y
Zebra Danio
Brachydanio rerio
Q7SXF1
478
55171
Y458
E
H
R
C
S
N
K
Y
G
K
D
W
E
R
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MLV1
741
83167
Y721
N
A
R
N
Q
A
R
Y
H
S
S
W
Q
R
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786536
578
65964
Y558
D
A
S
C
R
Q
K
Y
G
G
A
W
T
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDR4
369
41895
K350
V
R
C
A
E
K
Y
K
E
I
W
A
E
Y
L
Baker's Yeast
Sacchar. cerevisiae
P32462
438
50597
Y418
E
H
K
C
R
L
K
Y
G
E
N
W
E
E
Y
Red Bread Mold
Neurospora crassa
P38670
490
54704
Y470
D
E
K
C
S
K
K
Y
G
D
D
W
E
K
Y
Conservation
Percent
Protein Identity:
100
40.9
78
91.3
N.A.
86.1
41.4
N.A.
41
39
35.5
33
N.A.
20.9
N.A.
N.A.
39.1
Protein Similarity:
100
52.2
79.2
94.5
N.A.
91.3
51.7
N.A.
51.1
48.9
50.9
50.8
N.A.
33
N.A.
N.A.
48.2
P-Site Identity:
100
53.3
100
86.6
N.A.
86.6
66.6
N.A.
60
60
46.6
46.6
N.A.
26.6
N.A.
N.A.
53.3
P-Site Similarity:
100
80
100
93.3
N.A.
93.3
86.6
N.A.
80
73.3
60
60
N.A.
46.6
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
41.5
39.8
Protein Similarity:
N.A.
N.A.
N.A.
54.5
58.4
53.8
P-Site Identity:
N.A.
N.A.
N.A.
6.6
53.3
40
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
66.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
7
0
7
0
0
0
0
60
7
0
0
0
% A
% Cys:
0
0
7
87
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
0
0
0
0
0
0
7
20
0
0
0
0
% D
% Glu:
74
7
0
0
7
0
0
0
7
7
0
0
54
34
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
87
7
0
0
0
0
0
% G
% His:
0
34
20
0
0
0
0
0
7
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
14
0
20
34
87
7
0
14
0
0
7
34
0
% K
% Leu:
0
0
0
0
27
7
0
0
0
40
0
0
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
7
0
7
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
14
34
0
7
34
0
0
0
0
0
0
27
0
0
% Q
% Arg:
0
20
20
0
20
7
7
0
0
7
0
0
0
20
0
% R
% Ser:
0
0
7
0
20
7
0
0
0
7
7
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% T
% Val:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
94
0
0
0
% W
% Tyr:
0
7
0
0
0
0
7
94
0
0
0
0
0
7
94
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _