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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM7SF2
All Species:
46.97
Human Site:
Y405
Identified Species:
73.81
UniProt:
O76062
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76062
NP_003264.2
418
46406
Y405
Y
G
L
A
W
Q
E
Y
C
R
R
V
P
Y
R
Chimpanzee
Pan troglodytes
XP_514234
615
70705
Y602
Y
G
V
A
W
E
K
Y
R
Q
R
V
P
Y
R
Rhesus Macaque
Macaca mulatta
XP_001118188
516
56907
Y503
Y
G
L
A
W
Q
E
Y
C
R
R
V
P
Y
R
Dog
Lupus familis
XP_533236
418
46607
Y405
Y
G
L
A
W
H
E
Y
C
R
R
V
P
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q71KT5
418
46474
Y405
Y
G
R
A
W
Q
E
Y
C
K
R
V
P
Y
R
Rat
Rattus norvegicus
O08984
620
70706
Y607
Y
G
L
A
W
E
K
Y
C
Q
R
V
P
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514233
614
70236
Y601
Y
G
L
A
W
E
K
Y
C
Q
C
V
P
Y
R
Chicken
Gallus gallus
P23913
637
73480
Y595
Y
G
L
A
W
E
R
Y
C
Q
R
V
P
Y
T
Frog
Xenopus laevis
Q7ZXH1
473
54804
Y460
Y
G
K
D
W
K
L
Y
T
S
A
V
P
Y
R
Zebra Danio
Brachydanio rerio
Q7SXF1
478
55171
Y465
Y
G
K
D
W
E
R
Y
T
A
A
V
S
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MLV1
741
83167
Y728
Y
H
S
S
W
Q
R
Y
S
T
Q
V
R
S
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786536
578
65964
Y565
Y
G
G
A
W
T
K
Y
C
A
T
V
K
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDR4
369
41895
L357
K
E
I
W
A
E
Y
L
R
L
V
P
W
R
I
Baker's Yeast
Sacchar. cerevisiae
P32462
438
50597
Y425
Y
G
E
N
W
E
E
Y
E
R
K
V
P
Y
K
Red Bread Mold
Neurospora crassa
P38670
490
54704
Y477
Y
G
D
D
W
E
K
Y
K
K
L
V
K
W
R
Conservation
Percent
Protein Identity:
100
40.9
78
91.3
N.A.
86.1
41.4
N.A.
41
39
35.5
33
N.A.
20.9
N.A.
N.A.
39.1
Protein Similarity:
100
52.2
79.2
94.5
N.A.
91.3
51.7
N.A.
51.1
48.9
50.9
50.8
N.A.
33
N.A.
N.A.
48.2
P-Site Identity:
100
66.6
100
93.3
N.A.
86.6
80
N.A.
73.3
73.3
53.3
46.6
N.A.
33.3
N.A.
N.A.
60
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
100
N.A.
93.3
86.6
60
53.3
N.A.
46.6
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
41.5
39.8
Protein Similarity:
N.A.
N.A.
N.A.
54.5
58.4
53.8
P-Site Identity:
N.A.
N.A.
N.A.
0
60
40
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
80
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
60
7
0
0
0
0
14
14
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
54
0
7
0
0
0
0
% C
% Asp:
0
0
7
20
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
7
0
0
54
34
0
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
87
7
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
7
0
14
0
0
7
34
0
7
14
7
0
14
0
7
% K
% Leu:
0
0
40
0
0
0
7
7
0
7
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
67
0
0
% P
% Gln:
0
0
0
0
0
27
0
0
0
27
7
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
20
0
14
27
47
0
7
7
74
% R
% Ser:
0
0
7
7
0
0
0
0
7
7
0
0
7
7
0
% S
% Thr:
0
0
0
0
0
7
0
0
14
7
7
0
0
0
7
% T
% Val:
0
0
7
0
0
0
0
0
0
0
7
94
0
0
0
% V
% Trp:
0
0
0
7
94
0
0
0
0
0
0
0
7
7
0
% W
% Tyr:
94
0
0
0
0
0
7
94
0
0
0
0
0
80
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _