KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM7SF2
All Species:
44.24
Human Site:
Y411
Identified Species:
69.52
UniProt:
O76062
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76062
NP_003264.2
418
46406
Y411
E
Y
C
R
R
V
P
Y
R
I
M
P
Y
I
Y
Chimpanzee
Pan troglodytes
XP_514234
615
70705
Y608
K
Y
R
Q
R
V
P
Y
R
I
F
P
Y
I
Y
Rhesus Macaque
Macaca mulatta
XP_001118188
516
56907
Y509
E
Y
C
R
R
V
P
Y
R
I
V
P
Y
I
Y
Dog
Lupus familis
XP_533236
418
46607
Y411
E
Y
C
R
R
V
P
Y
R
I
L
P
Y
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q71KT5
418
46474
Y411
E
Y
C
K
R
V
P
Y
R
I
I
P
Y
V
Y
Rat
Rattus norvegicus
O08984
620
70706
Y613
K
Y
C
Q
R
V
P
Y
R
I
F
P
Y
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514233
614
70236
Y607
K
Y
C
Q
C
V
P
Y
R
I
F
P
Y
I
Y
Chicken
Gallus gallus
P23913
637
73480
Y601
R
Y
C
Q
R
V
P
Y
T
H
I
S
L
H
L
Frog
Xenopus laevis
Q7ZXH1
473
54804
Y466
L
Y
T
S
A
V
P
Y
R
L
L
P
G
L
F
Zebra Danio
Brachydanio rerio
Q7SXF1
478
55171
Y471
R
Y
T
A
A
V
S
Y
R
L
L
P
N
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MLV1
741
83167
S734
R
Y
S
T
Q
V
R
S
Y
I
L
P
R
V
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786536
578
65964
Y571
K
Y
C
A
T
V
K
Y
R
I
I
P
Y
I
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDR4
369
41895
Baker's Yeast
Sacchar. cerevisiae
P32462
438
50597
Y431
E
Y
E
R
K
V
P
Y
K
I
I
P
Y
V
Y
Red Bread Mold
Neurospora crassa
P38670
490
54704
W483
K
Y
K
K
L
V
K
W
R
I
V
P
G
I
Y
Conservation
Percent
Protein Identity:
100
40.9
78
91.3
N.A.
86.1
41.4
N.A.
41
39
35.5
33
N.A.
20.9
N.A.
N.A.
39.1
Protein Similarity:
100
52.2
79.2
94.5
N.A.
91.3
51.7
N.A.
51.1
48.9
50.9
50.8
N.A.
33
N.A.
N.A.
48.2
P-Site Identity:
100
73.3
93.3
93.3
N.A.
80
80
N.A.
73.3
40
40
40
N.A.
33.3
N.A.
N.A.
66.6
P-Site Similarity:
100
86.6
100
100
N.A.
100
93.3
N.A.
86.6
53.3
66.6
60
N.A.
53.3
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
41.5
39.8
Protein Similarity:
N.A.
N.A.
N.A.
54.5
58.4
53.8
P-Site Identity:
N.A.
N.A.
N.A.
0
66.6
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
0
93.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
14
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
54
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
34
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
14
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
74
27
0
0
60
0
% I
% Lys:
34
0
7
14
7
0
14
0
7
0
0
0
0
0
0
% K
% Leu:
7
0
0
0
7
0
0
0
0
14
27
0
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
67
0
0
0
0
87
0
0
0
% P
% Gln:
0
0
0
27
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
20
0
7
27
47
0
7
0
74
0
0
0
7
0
0
% R
% Ser:
0
0
7
7
0
0
7
7
0
0
0
7
0
0
0
% S
% Thr:
0
0
14
7
7
0
0
0
7
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
94
0
0
0
0
14
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
94
0
0
0
0
0
80
7
0
0
0
60
0
74
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _