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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM7SF2
All Species:
34.24
Human Site:
Y98
Identified Species:
53.81
UniProt:
O76062
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76062
NP_003264.2
418
46406
Y98
K
D
K
S
R
L
R
Y
P
I
N
G
F
Q
A
Chimpanzee
Pan troglodytes
XP_514234
615
70705
Y294
I
D
G
R
R
L
K
Y
R
L
N
G
F
Y
A
Rhesus Macaque
Macaca mulatta
XP_001118188
516
56907
Y196
K
D
K
S
R
L
R
Y
P
I
N
G
F
Q
A
Dog
Lupus familis
XP_533236
418
46607
Y98
K
D
K
S
R
L
L
Y
P
I
N
G
F
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q71KT5
418
46474
Y98
K
D
K
S
R
L
R
Y
P
I
N
G
F
Q
A
Rat
Rattus norvegicus
O08984
620
70706
Y299
V
D
G
R
R
L
K
Y
R
L
N
G
L
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514233
614
70236
Y293
L
S
G
R
R
L
K
Y
R
I
N
G
F
Y
A
Chicken
Gallus gallus
P23913
637
73480
Y286
S
N
P
R
K
L
Q
Y
R
I
N
G
F
Y
A
Frog
Xenopus laevis
Q7ZXH1
473
54804
Y141
P
A
G
L
I
N
K
Y
Q
V
N
G
L
Q
A
Zebra Danio
Brachydanio rerio
Q7SXF1
478
55171
M115
T
F
Q
V
V
L
Y
M
C
V
P
D
F
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MLV1
741
83167
V400
Y
K
F
N
C
L
A
V
S
L
T
L
L
I
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786536
578
65964
Y257
R
S
G
Q
R
L
S
Y
R
T
N
G
L
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDR4
369
41895
D83
V
S
P
L
V
V
A
D
R
G
L
E
L
L
S
Baker's Yeast
Sacchar. cerevisiae
P32462
438
50597
Y108
R
D
G
S
K
L
S
Y
K
I
N
G
I
A
M
Red Bread Mold
Neurospora crassa
P38670
490
54704
Y124
S
T
G
G
R
L
K
Y
K
L
N
A
F
N
S
Conservation
Percent
Protein Identity:
100
40.9
78
91.3
N.A.
86.1
41.4
N.A.
41
39
35.5
33
N.A.
20.9
N.A.
N.A.
39.1
Protein Similarity:
100
52.2
79.2
94.5
N.A.
91.3
51.7
N.A.
51.1
48.9
50.9
50.8
N.A.
33
N.A.
N.A.
48.2
P-Site Identity:
100
53.3
100
93.3
N.A.
100
46.6
N.A.
53.3
46.6
33.3
13.3
N.A.
13.3
N.A.
N.A.
40
P-Site Similarity:
100
66.6
100
93.3
N.A.
100
60
N.A.
60
66.6
46.6
26.6
N.A.
26.6
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
41.5
39.8
Protein Similarity:
N.A.
N.A.
N.A.
54.5
58.4
53.8
P-Site Identity:
N.A.
N.A.
N.A.
0
46.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
60
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
14
0
0
0
0
7
0
7
74
% A
% Cys:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
47
0
0
0
0
0
7
0
0
0
7
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% E
% Phe:
0
7
7
0
0
0
0
0
0
0
0
0
60
7
0
% F
% Gly:
0
0
47
7
0
0
0
0
0
7
0
74
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
0
0
7
0
0
0
0
47
0
0
7
7
0
% I
% Lys:
27
7
27
0
14
0
34
0
14
0
0
0
0
0
0
% K
% Leu:
7
0
0
14
0
87
7
0
0
27
7
7
34
14
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% M
% Asn:
0
7
0
7
0
7
0
0
0
0
80
0
0
7
0
% N
% Pro:
7
0
14
0
0
0
0
0
27
0
7
0
0
0
0
% P
% Gln:
0
0
7
7
0
0
7
0
7
0
0
0
0
34
0
% Q
% Arg:
14
0
0
27
60
0
20
0
40
0
0
0
0
0
0
% R
% Ser:
14
20
0
34
0
0
14
0
7
0
0
0
0
0
14
% S
% Thr:
7
7
0
0
0
0
0
0
0
7
7
0
0
0
0
% T
% Val:
14
0
0
7
14
7
0
7
0
14
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
80
0
0
0
0
0
27
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _