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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF8
All Species:
10.61
Human Site:
S183
Identified Species:
23.33
UniProt:
O76064
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76064
NP_003949.1
485
55518
S183
I
N
K
V
S
C
E
S
G
Q
P
V
K
S
Q
Chimpanzee
Pan troglodytes
XP_527377
1353
154542
S265
I
N
K
V
S
C
E
S
G
Q
S
V
K
S
Q
Rhesus Macaque
Macaca mulatta
XP_001117035
1272
145662
S183
I
N
K
V
S
C
E
S
S
Q
S
V
K
S
Q
Dog
Lupus familis
XP_864730
487
55889
P183
I
S
K
V
S
Y
K
P
G
Q
P
V
K
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC56
488
55498
P183
L
A
N
V
A
S
K
P
I
E
P
E
K
L
H
Rat
Rattus norvegicus
Q4KLN8
487
55596
P183
L
A
K
G
S
S
K
P
A
E
P
E
K
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511244
573
64796
A182
P
G
P
S
R
E
P
A
A
G
A
C
D
S
L
Chicken
Gallus gallus
XP_419487
523
59609
V184
L
S
N
L
L
G
R
V
G
E
A
K
Q
L
T
Frog
Xenopus laevis
Q7ZX20
540
61907
T198
V
E
P
T
A
S
G
T
E
S
R
L
N
D
S
Zebra Danio
Brachydanio rerio
Q803C1
485
55307
T204
P
S
G
E
R
R
E
T
L
K
L
S
S
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788216
558
65220
L216
K
R
L
Q
E
E
A
L
E
T
Q
K
R
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.8
36.7
85.2
N.A.
70.9
72.9
N.A.
46.4
53.9
44.8
41.4
N.A.
N.A.
N.A.
N.A.
23.1
Protein Similarity:
100
34.8
37.6
91.7
N.A.
81.9
82.9
N.A.
58.8
68.6
57.9
61.2
N.A.
N.A.
N.A.
N.A.
40.5
P-Site Identity:
100
93.3
86.6
66.6
N.A.
20
26.6
N.A.
6.6
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
86.6
80
N.A.
46.6
46.6
N.A.
13.3
40
26.6
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
19
0
10
10
19
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
28
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% D
% Glu:
0
10
0
10
10
19
37
0
19
28
0
19
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
10
0
10
10
0
37
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
28
% H
% Ile:
37
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
0
46
0
0
0
28
0
0
10
0
19
55
0
0
% K
% Leu:
28
0
10
10
10
0
0
10
10
0
10
10
0
37
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
28
19
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
19
0
19
0
0
0
10
28
0
0
37
0
0
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
37
10
0
10
0
28
% Q
% Arg:
0
10
0
0
19
10
10
0
0
0
10
0
10
10
0
% R
% Ser:
0
28
0
10
46
28
0
28
10
10
19
10
10
46
10
% S
% Thr:
0
0
0
10
0
0
0
19
0
10
0
0
0
0
10
% T
% Val:
10
0
0
46
0
0
0
10
0
0
0
37
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _