KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF8
All Species:
8.18
Human Site:
S245
Identified Species:
18
UniProt:
O76064
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76064
NP_003949.1
485
55518
S245
N
S
S
A
S
Q
R
S
L
Q
M
F
K
V
T
Chimpanzee
Pan troglodytes
XP_527377
1353
154542
S327
N
S
S
A
S
Q
R
S
L
Q
M
F
K
V
T
Rhesus Macaque
Macaca mulatta
XP_001117035
1272
145662
R245
S
N
S
S
A
S
Q
R
S
L
Q
M
F
K
V
Dog
Lupus familis
XP_864730
487
55889
Q245
A
S
S
P
S
A
S
Q
S
S
L
E
L
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC56
488
55498
S245
K
A
C
R
P
S
A
S
Q
N
S
L
E
L
F
Rat
Rattus norvegicus
Q4KLN8
487
55596
Q245
A
C
S
P
S
A
S
Q
S
S
L
E
L
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511244
573
64796
Q244
K
Q
Q
K
K
G
A
Q
K
A
V
V
K
M
E
Chicken
Gallus gallus
XP_419487
523
59609
K246
T
D
L
E
N
L
R
K
T
L
I
D
I
K
K
Frog
Xenopus laevis
Q7ZX20
540
61907
V260
N
S
P
L
E
N
Q
V
G
A
N
S
V
L
A
Zebra Danio
Brachydanio rerio
Q803C1
485
55307
Q266
E
L
E
Q
Q
Q
T
Q
T
P
E
R
E
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788216
558
65220
S278
D
T
S
L
Q
E
F
S
K
Q
L
A
E
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.8
36.7
85.2
N.A.
70.9
72.9
N.A.
46.4
53.9
44.8
41.4
N.A.
N.A.
N.A.
N.A.
23.1
Protein Similarity:
100
34.8
37.6
91.7
N.A.
81.9
82.9
N.A.
58.8
68.6
57.9
61.2
N.A.
N.A.
N.A.
N.A.
40.5
P-Site Identity:
100
100
6.6
20
N.A.
6.6
13.3
N.A.
6.6
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
40
26.6
N.A.
26.6
20
N.A.
20
20
26.6
13.3
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
19
10
19
19
0
0
19
0
10
0
0
10
% A
% Cys:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% D
% Glu:
10
0
10
10
10
10
0
0
0
0
10
19
28
0
19
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
19
10
19
10
% F
% Gly:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% I
% Lys:
19
0
0
10
10
0
0
10
19
0
0
0
28
37
28
% K
% Leu:
0
10
10
19
0
10
0
0
19
19
28
10
19
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
19
10
0
10
0
% M
% Asn:
28
10
0
0
10
10
0
0
0
10
10
0
0
0
0
% N
% Pro:
0
0
10
19
10
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
10
10
10
19
28
19
37
10
28
10
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
28
10
0
0
0
10
0
0
0
% R
% Ser:
10
37
55
10
37
19
19
37
28
19
10
10
0
0
0
% S
% Thr:
10
10
0
0
0
0
10
0
19
0
0
0
0
0
19
% T
% Val:
0
0
0
0
0
0
0
10
0
0
10
10
10
19
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _