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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF8
All Species:
34.24
Human Site:
S357
Identified Species:
75.33
UniProt:
O76064
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76064
NP_003949.1
485
55518
S357
L
M
E
E
L
N
R
S
K
K
D
F
E
A
I
Chimpanzee
Pan troglodytes
XP_527377
1353
154542
S439
L
M
E
E
L
N
R
S
K
K
D
F
E
A
I
Rhesus Macaque
Macaca mulatta
XP_001117035
1272
145662
S358
L
M
E
E
L
N
R
S
K
K
D
F
E
A
I
Dog
Lupus familis
XP_864730
487
55889
S359
L
M
E
E
L
N
R
S
K
K
D
F
E
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC56
488
55498
S360
L
M
E
E
L
N
C
S
K
K
D
F
E
K
I
Rat
Rattus norvegicus
Q4KLN8
487
55596
S359
L
M
E
E
L
D
R
S
K
K
D
F
E
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511244
573
64796
S319
L
M
E
E
L
S
R
S
K
S
D
F
E
A
I
Chicken
Gallus gallus
XP_419487
523
59609
S352
L
M
E
E
L
S
R
S
K
K
D
F
E
E
I
Frog
Xenopus laevis
Q7ZX20
540
61907
S336
L
M
Q
E
L
N
R
S
K
N
D
F
E
Q
I
Zebra Danio
Brachydanio rerio
Q803C1
485
55307
A346
V
I
E
E
L
K
H
A
W
Q
G
F
K
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788216
558
65220
E359
I
I
Q
Q
K
E
K
E
K
T
D
M
E
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.8
36.7
85.2
N.A.
70.9
72.9
N.A.
46.4
53.9
44.8
41.4
N.A.
N.A.
N.A.
N.A.
23.1
Protein Similarity:
100
34.8
37.6
91.7
N.A.
81.9
82.9
N.A.
58.8
68.6
57.9
61.2
N.A.
N.A.
N.A.
N.A.
40.5
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
86.6
86.6
80
26.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
93.3
93.3
86.6
66.6
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
46
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
91
0
0
10
0
% D
% Glu:
0
0
82
91
0
10
0
10
0
0
0
0
91
19
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
91
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
10
19
0
0
0
0
0
0
0
0
0
0
0
0
82
% I
% Lys:
0
0
0
0
10
10
10
0
91
64
0
0
10
19
0
% K
% Leu:
82
0
0
0
91
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
82
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
55
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
19
10
0
0
0
0
0
10
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
73
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
19
0
82
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _