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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF8 All Species: 21.21
Human Site: T152 Identified Species: 46.67
UniProt: O76064 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76064 NP_003949.1 485 55518 T152 E K N K E L R T K R K F S L D
Chimpanzee Pan troglodytes XP_527377 1353 154542 T234 E K N K E L R T K R K F S L D
Rhesus Macaque Macaca mulatta XP_001117035 1272 145662 T152 E K N K E L R T K R K F S L D
Dog Lupus familis XP_864730 487 55889 T152 G K N R G L R T K R K F S L D
Cat Felis silvestris
Mouse Mus musculus Q8VC56 488 55498 T152 E K H K G S R T K R K F S S P
Rat Rattus norvegicus Q4KLN8 487 55596 T152 E K H K G L R T K R K F S S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511244 573 64796 L151 L C I L L S D L E P P G R H W
Chicken Gallus gallus XP_419487 523 59609 E153 K F T S E E S E T S G S E G P
Frog Xenopus laevis Q7ZX20 540 61907 Y167 N F S I P K F Y R V S R E D E
Zebra Danio Brachydanio rerio Q803C1 485 55307 C173 G G D E S E P C P T Q H S K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788216 558 65220 V185 E K N A K L E V E Y K T R V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.8 36.7 85.2 N.A. 70.9 72.9 N.A. 46.4 53.9 44.8 41.4 N.A. N.A. N.A. N.A. 23.1
Protein Similarity: 100 34.8 37.6 91.7 N.A. 81.9 82.9 N.A. 58.8 68.6 57.9 61.2 N.A. N.A. N.A. N.A. 40.5
P-Site Identity: 100 100 100 80 N.A. 66.6 80 N.A. 0 6.6 0 6.6 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 100 86.6 N.A. 73.3 86.6 N.A. 6.6 13.3 20 26.6 N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 10 0 0 0 0 0 0 10 46 % D
% Glu: 55 0 0 10 37 19 10 10 19 0 0 0 19 0 19 % E
% Phe: 0 19 0 0 0 0 10 0 0 0 0 55 0 0 0 % F
% Gly: 19 10 0 0 28 0 0 0 0 0 10 10 0 10 0 % G
% His: 0 0 19 0 0 0 0 0 0 0 0 10 0 10 0 % H
% Ile: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 64 0 46 10 10 0 0 55 0 64 0 0 10 0 % K
% Leu: 10 0 0 10 10 55 0 10 0 0 0 0 0 37 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 46 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 10 0 10 10 10 0 0 0 19 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 10 0 0 55 0 10 55 0 10 19 0 0 % R
% Ser: 0 0 10 10 10 19 10 0 0 10 10 10 64 19 10 % S
% Thr: 0 0 10 0 0 0 0 55 10 10 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _