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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF8
All Species:
10.3
Human Site:
T198
Identified Species:
22.67
UniProt:
O76064
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76064
NP_003949.1
485
55518
T198
G
K
G
E
V
A
S
T
P
S
D
N
L
D
P
Chimpanzee
Pan troglodytes
XP_527377
1353
154542
T280
G
K
G
E
V
A
S
T
P
S
D
N
L
D
P
Rhesus Macaque
Macaca mulatta
XP_001117035
1272
145662
T198
G
K
G
E
V
A
S
T
P
S
E
N
L
D
P
Dog
Lupus familis
XP_864730
487
55889
Q198
G
K
G
E
V
A
S
Q
P
S
E
Y
L
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC56
488
55498
Q198
G
K
G
D
A
S
S
Q
S
L
G
C
L
C
P
Rat
Rattus norvegicus
Q4KLN8
487
55596
Q198
G
K
G
E
A
A
S
Q
P
L
G
C
L
C
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511244
573
64796
S197
R
R
K
T
A
A
P
S
P
R
G
P
D
A
S
Chicken
Gallus gallus
XP_419487
523
59609
P199
D
K
V
D
V
K
L
P
S
P
G
S
S
E
G
Frog
Xenopus laevis
Q7ZX20
540
61907
P213
V
E
A
E
V
V
A
P
T
Q
Q
Q
C
R
S
Zebra Danio
Brachydanio rerio
Q803C1
485
55307
A219
L
E
E
D
R
D
K
A
G
S
S
S
S
T
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788216
558
65220
A231
E
E
K
E
E
A
L
A
K
M
K
Q
E
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.8
36.7
85.2
N.A.
70.9
72.9
N.A.
46.4
53.9
44.8
41.4
N.A.
N.A.
N.A.
N.A.
23.1
Protein Similarity:
100
34.8
37.6
91.7
N.A.
81.9
82.9
N.A.
58.8
68.6
57.9
61.2
N.A.
N.A.
N.A.
N.A.
40.5
P-Site Identity:
100
100
93.3
80
N.A.
40
60
N.A.
13.3
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
53.3
60
N.A.
26.6
33.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
28
64
10
19
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
19
10
19
10
% C
% Asp:
10
0
0
28
0
10
0
0
0
0
19
0
10
37
0
% D
% Glu:
10
28
10
64
10
0
0
0
0
0
19
0
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
55
0
55
0
0
0
0
0
10
0
37
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
64
19
0
0
10
10
0
10
0
10
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
19
0
0
19
0
0
55
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
19
55
10
0
10
0
0
55
% P
% Gln:
0
0
0
0
0
0
0
28
0
10
10
19
0
0
0
% Q
% Arg:
10
10
0
0
10
0
0
0
0
10
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
10
55
10
19
46
10
19
19
0
19
% S
% Thr:
0
0
0
10
0
0
0
28
10
0
0
0
0
10
0
% T
% Val:
10
0
10
0
55
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _