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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF8
All Species:
14.55
Human Site:
Y133
Identified Species:
32
UniProt:
O76064
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76064
NP_003949.1
485
55518
Y133
E
E
D
W
E
T
I
Y
P
C
L
S
P
K
N
Chimpanzee
Pan troglodytes
XP_527377
1353
154542
Y215
E
E
D
W
E
T
I
Y
P
C
L
S
P
K
N
Rhesus Macaque
Macaca mulatta
XP_001117035
1272
145662
Y133
E
E
D
W
E
T
I
Y
P
C
L
S
P
K
N
Dog
Lupus familis
XP_864730
487
55889
Y133
E
E
D
W
E
R
M
Y
P
C
L
A
P
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC56
488
55498
A133
E
E
D
W
E
S
L
A
P
C
L
A
P
K
N
Rat
Rattus norvegicus
Q4KLN8
487
55596
A133
E
E
D
R
E
S
L
A
P
C
L
A
P
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511244
573
64796
P132
D
G
G
K
W
E
A
P
G
T
E
G
P
S
S
Chicken
Gallus gallus
XP_419487
523
59609
D134
P
F
L
A
Q
R
S
D
L
G
K
A
R
S
S
Frog
Xenopus laevis
Q7ZX20
540
61907
E148
T
K
R
K
F
T
S
E
D
T
D
A
S
G
N
Zebra Danio
Brachydanio rerio
Q803C1
485
55307
S154
D
S
G
A
A
S
L
S
Q
K
L
K
N
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788216
558
65220
L166
G
E
S
V
L
D
R
L
K
S
T
V
K
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.8
36.7
85.2
N.A.
70.9
72.9
N.A.
46.4
53.9
44.8
41.4
N.A.
N.A.
N.A.
N.A.
23.1
Protein Similarity:
100
34.8
37.6
91.7
N.A.
81.9
82.9
N.A.
58.8
68.6
57.9
61.2
N.A.
N.A.
N.A.
N.A.
40.5
P-Site Identity:
100
100
100
80
N.A.
73.3
66.6
N.A.
6.6
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
20
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
10
0
10
19
0
0
0
46
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
55
0
0
0
0
0
% C
% Asp:
19
0
55
0
0
10
0
10
10
0
10
0
0
0
0
% D
% Glu:
55
64
0
0
55
10
0
10
0
0
10
0
0
0
0
% E
% Phe:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
19
0
0
0
0
0
10
10
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
19
0
0
0
0
10
10
10
10
10
64
10
% K
% Leu:
0
0
10
0
10
0
28
10
10
0
64
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
64
% N
% Pro:
10
0
0
0
0
0
0
10
55
0
0
0
64
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
10
% Q
% Arg:
0
0
10
10
0
19
10
0
0
0
0
0
10
0
0
% R
% Ser:
0
10
10
0
0
28
19
10
0
10
0
28
10
28
19
% S
% Thr:
10
0
0
0
0
37
0
0
0
19
10
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
46
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _