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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIAO1
All Species:
32.73
Human Site:
S110
Identified Species:
48
UniProt:
O76071
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76071
NP_004795.1
339
37840
S110
G
H
E
N
E
V
K
S
V
A
W
A
P
S
G
Chimpanzee
Pan troglodytes
XP_001144741
472
51924
S243
G
H
E
N
E
V
K
S
V
A
W
A
P
S
G
Rhesus Macaque
Macaca mulatta
XP_001098395
339
37880
S110
G
H
E
N
E
V
K
S
V
A
W
A
P
S
G
Dog
Lupus familis
XP_532950
339
37846
S110
G
H
E
N
E
V
K
S
V
A
W
A
P
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99KN2
339
37614
S110
G
H
E
N
E
V
K
S
V
A
W
A
P
S
G
Rat
Rattus norvegicus
Q5M7T1
339
37599
S110
G
H
E
N
E
V
K
S
V
A
W
A
P
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517379
223
24600
Chicken
Gallus gallus
XP_423992
209
23301
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0D9
330
36784
N106
T
V
L
E
G
H
E
N
E
V
K
C
V
A
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K1Y4
335
37026
S110
E
N
E
V
K
S
V
S
W
S
R
S
G
G
L
Honey Bee
Apis mellifera
XP_395314
332
37365
S108
G
H
E
N
E
V
K
S
V
S
W
S
C
S
G
Nematode Worm
Caenorhab. elegans
Q9XW12
337
38172
E111
V
N
K
L
E
G
H
E
S
E
V
K
C
A
V
Sea Urchin
Strong. purpuratus
XP_781960
340
38037
V110
H
E
N
E
V
K
S
V
A
W
S
Q
S
G
S
Poplar Tree
Populus trichocarpa
XP_002299788
323
35737
V99
L
E
G
H
E
N
E
V
K
C
V
S
W
N
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565615
352
39113
S123
G
H
E
N
E
V
K
S
V
S
W
N
A
S
G
Baker's Yeast
Sacchar. cerevisiae
Q05583
330
37256
H106
L
L
A
I
I
E
G
H
E
N
E
V
K
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
99.7
97.3
N.A.
94.9
94.4
N.A.
50.1
51.6
N.A.
76.1
N.A.
58.1
58.4
38.6
60
Protein Similarity:
100
71.8
99.7
98.8
N.A.
97.9
97.3
N.A.
54.2
57.5
N.A.
85.8
N.A.
72.2
75.5
57.2
75.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
0
N.A.
0
N.A.
13.3
80
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
0
N.A.
20
N.A.
40
93.3
26.6
0
Percent
Protein Identity:
49.2
N.A.
N.A.
48
41.8
N.A.
Protein Similarity:
63.4
N.A.
N.A.
64.7
59.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
80
0
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
86.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
7
38
0
38
7
13
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
7
13
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
13
57
13
63
7
13
7
13
7
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
7
0
7
7
7
0
0
0
0
0
7
19
50
% G
% His:
7
50
0
7
0
7
7
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
7
0
7
7
50
0
7
0
7
7
7
0
0
% K
% Leu:
13
7
7
7
0
0
0
0
0
0
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
7
50
0
7
0
7
0
7
0
7
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
7
57
7
19
7
19
7
50
7
% S
% Thr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
7
0
7
7
50
7
13
50
7
13
7
7
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
7
7
50
0
7
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _