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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIAO1
All Species:
28.18
Human Site:
S285
Identified Species:
41.33
UniProt:
O76071
Number Species:
15
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76071
NP_004795.1
339
37840
S285
V
F
Q
E
D
P
N
S
D
P
Q
Q
P
T
F
Chimpanzee
Pan troglodytes
XP_001144741
472
51924
S418
V
F
Q
E
D
P
N
S
D
P
Q
Q
P
T
F
Rhesus Macaque
Macaca mulatta
XP_001098395
339
37880
S285
V
F
Q
E
D
P
N
S
D
P
Q
Q
P
T
F
Dog
Lupus familis
XP_532950
339
37846
S285
V
F
E
E
D
P
S
S
D
P
Q
Q
P
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q99KN2
339
37614
S285
V
F
E
E
D
P
G
S
D
P
Q
Q
P
T
F
Rat
Rattus norvegicus
Q5M7T1
339
37599
S285
V
F
E
E
D
P
G
S
D
P
Q
Q
P
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517379
223
24600
A173
D
P
T
G
Q
R
L
A
T
C
S
D
D
R
T
Chicken
Gallus gallus
XP_423992
209
23301
Q159
S
P
Q
Q
Q
Q
Q
Q
P
T
F
S
L
T
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0D9
330
36784
D280
F
S
E
D
P
T
A
D
P
E
Q
P
I
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K1Y4
335
37026
S285
I
F
K
E
S
S
D
S
K
P
D
E
P
T
F
Honey Bee
Apis mellifera
XP_395314
332
37365
S282
I
R
I
F
K
E
D
S
D
S
D
P
H
Q
P
Nematode Worm
Caenorhab. elegans
Q9XW12
337
38172
S285
K
I
R
L
F
K
I
S
S
T
P
E
S
P
V
Sea Urchin
Strong. purpuratus
XP_781960
340
38037
D287
K
E
D
E
S
I
Q
D
R
R
N
Q
P
T
F
Poplar Tree
Populus trichocarpa
XP_002299788
323
35737
S273
A
L
R
F
F
V
E
S
K
D
G
L
V
D
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565615
352
39113
D299
L
F
V
D
S
K
H
D
S
V
D
G
P
S
Y
Baker's Yeast
Sacchar. cerevisiae
Q05583
330
37256
D280
L
A
V
Y
E
E
V
D
G
E
W
K
V
F
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
99.7
97.3
N.A.
94.9
94.4
N.A.
50.1
51.6
N.A.
76.1
N.A.
58.1
58.4
38.6
60
Protein Similarity:
100
71.8
99.7
98.8
N.A.
97.9
97.3
N.A.
54.2
57.5
N.A.
85.8
N.A.
72.2
75.5
57.2
75.8
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
0
13.3
N.A.
6.6
N.A.
46.6
13.3
6.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
6.6
20
N.A.
20
N.A.
73.3
26.6
20
33.3
Percent
Protein Identity:
49.2
N.A.
N.A.
48
41.8
N.A.
Protein Similarity:
63.4
N.A.
N.A.
64.7
59.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
7
7
0
0
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
0
7
13
38
0
13
25
44
7
19
7
7
7
0
% D
% Glu:
0
7
25
50
7
13
7
0
0
13
0
13
0
0
0
% E
% Phe:
7
50
0
13
13
0
0
0
0
0
7
0
0
13
50
% F
% Gly:
0
0
0
7
0
0
13
0
7
0
7
7
0
0
7
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% H
% Ile:
13
7
7
0
0
7
7
0
0
0
0
0
7
0
0
% I
% Lys:
13
0
7
0
7
13
0
0
13
0
0
7
0
0
0
% K
% Leu:
13
7
0
7
0
0
7
0
0
0
0
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
19
0
0
0
7
0
0
0
0
% N
% Pro:
0
13
0
0
7
38
0
0
13
44
7
13
57
7
7
% P
% Gln:
0
0
25
7
13
7
13
7
0
0
44
44
0
7
0
% Q
% Arg:
0
7
13
0
0
7
0
0
7
7
0
0
0
7
0
% R
% Ser:
7
7
0
0
19
7
7
63
13
7
7
7
7
7
0
% S
% Thr:
0
0
7
0
0
7
0
0
7
13
0
0
0
57
7
% T
% Val:
38
0
13
0
0
7
7
0
0
7
0
0
13
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _