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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIAO1
All Species:
30
Human Site:
T173
Identified Species:
44
UniProt:
O76071
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76071
NP_004795.1
339
37840
T173
A
S
A
S
Y
D
D
T
V
K
L
Y
R
E
E
Chimpanzee
Pan troglodytes
XP_001144741
472
51924
T306
A
S
A
S
Y
D
D
T
V
K
L
Y
R
E
E
Rhesus Macaque
Macaca mulatta
XP_001098395
339
37880
T173
A
S
A
S
Y
D
D
T
V
K
L
Y
R
E
E
Dog
Lupus familis
XP_532950
339
37846
T173
A
S
A
S
Y
D
D
T
V
K
L
Y
R
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99KN2
339
37614
T173
A
S
A
S
Y
D
D
T
V
K
L
Y
Q
E
E
Rat
Rattus norvegicus
Q5M7T1
339
37599
T173
A
S
A
S
Y
D
D
T
V
K
L
Y
Q
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517379
223
24600
A62
A
G
G
R
G
C
V
A
T
L
E
G
H
E
N
Chicken
Gallus gallus
XP_423992
209
23301
D48
K
L
Y
H
E
E
E
D
D
W
V
C
C
A
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0D9
330
36784
S169
Q
E
L
L
A
S
A
S
Y
D
N
K
I
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K1Y4
335
37026
K173
A
S
Y
D
N
T
I
K
M
F
A
E
E
P
I
Honey Bee
Apis mellifera
XP_395314
332
37365
V171
S
A
S
Y
D
N
T
V
K
I
F
K
E
D
I
Nematode Worm
Caenorhab. elegans
Q9XW12
337
38172
C174
T
E
D
L
L
V
S
C
S
Y
D
S
S
I
R
Sea Urchin
Strong. purpuratus
XP_781960
340
38037
T173
A
S
C
S
Y
D
N
T
I
R
F
F
H
E
E
Poplar Tree
Populus trichocarpa
XP_002299788
323
35737
D162
V
L
F
S
C
S
Y
D
N
T
V
K
V
W
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565615
352
39113
T186
F
S
C
S
Y
D
N
T
I
K
V
W
W
S
E
Baker's Yeast
Sacchar. cerevisiae
Q05583
330
37256
A169
H
P
S
E
A
L
L
A
S
S
S
Y
D
D
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
99.7
97.3
N.A.
94.9
94.4
N.A.
50.1
51.6
N.A.
76.1
N.A.
58.1
58.4
38.6
60
Protein Similarity:
100
71.8
99.7
98.8
N.A.
97.9
97.3
N.A.
54.2
57.5
N.A.
85.8
N.A.
72.2
75.5
57.2
75.8
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
0
N.A.
0
N.A.
13.3
0
0
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
20
N.A.
6.6
N.A.
20
33.3
0
80
Percent
Protein Identity:
49.2
N.A.
N.A.
48
41.8
N.A.
Protein Similarity:
63.4
N.A.
N.A.
64.7
59.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
46.6
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
73.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
57
7
38
0
13
0
7
13
0
0
7
0
0
7
7
% A
% Cys:
0
0
13
0
7
7
0
7
0
0
0
7
7
7
0
% C
% Asp:
0
0
7
7
7
50
38
13
7
7
7
0
7
13
0
% D
% Glu:
0
13
0
7
7
7
7
0
0
0
7
7
13
50
50
% E
% Phe:
7
0
7
0
0
0
0
0
0
7
13
7
0
0
0
% F
% Gly:
0
7
7
0
7
0
0
0
0
0
0
7
0
0
0
% G
% His:
7
0
0
7
0
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
13
7
0
0
7
7
19
% I
% Lys:
7
0
0
0
0
0
0
7
7
44
0
19
0
0
0
% K
% Leu:
0
13
7
13
7
7
7
0
0
7
38
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
7
13
0
7
0
7
0
0
0
7
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
7
0
0
25
0
7
% R
% Ser:
7
57
13
57
0
13
7
7
13
7
7
7
7
7
0
% S
% Thr:
7
0
0
0
0
7
7
50
7
7
0
0
0
0
13
% T
% Val:
7
0
0
0
0
7
7
7
38
0
19
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
7
7
7
0
% W
% Tyr:
0
0
13
7
50
0
7
0
7
7
0
44
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _