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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIAO1
All Species:
32.73
Human Site:
T217
Identified Species:
48
UniProt:
O76071
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76071
NP_004795.1
339
37840
T217
A
S
C
S
D
D
R
T
V
R
I
W
R
Q
Y
Chimpanzee
Pan troglodytes
XP_001144741
472
51924
T350
A
S
C
S
D
D
R
T
V
R
I
W
R
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001098395
339
37880
T217
A
S
C
S
D
D
R
T
V
R
I
W
R
Q
Y
Dog
Lupus familis
XP_532950
339
37846
T217
A
S
C
S
D
D
R
T
V
R
I
W
R
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q99KN2
339
37614
T217
A
S
C
S
D
D
R
T
V
R
I
W
R
Q
Y
Rat
Rattus norvegicus
Q5M7T1
339
37599
T217
A
S
C
S
D
D
R
T
V
R
I
W
R
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517379
223
24600
V106
E
E
D
E
Y
E
C
V
S
V
L
N
S
H
T
Chicken
Gallus gallus
XP_423992
209
23301
P92
R
I
W
Q
C
Y
R
P
G
N
E
E
G
V
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0D9
330
36784
S213
G
R
R
L
A
S
C
S
D
D
R
T
V
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K1Y4
335
37026
T217
V
S
C
S
D
D
T
T
I
K
I
W
R
A
Y
Honey Bee
Apis mellifera
XP_395314
332
37365
Q215
I
A
T
C
S
D
D
Q
T
V
K
I
W
Q
E
Nematode Worm
Caenorhab. elegans
Q9XW12
337
38172
T218
T
E
G
H
R
L
V
T
V
G
E
D
H
C
I
Sea Urchin
Strong. purpuratus
XP_781960
340
38037
T217
A
S
S
S
D
D
K
T
V
K
I
W
Q
E
Y
Poplar Tree
Populus trichocarpa
XP_002299788
323
35737
V206
N
A
E
G
N
R
M
V
T
C
S
D
D
L
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565615
352
39113
T230
A
A
G
D
K
M
V
T
C
S
D
D
L
T
L
Baker's Yeast
Sacchar. cerevisiae
Q05583
330
37256
R213
D
K
T
E
G
V
F
R
L
C
S
G
S
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
99.7
97.3
N.A.
94.9
94.4
N.A.
50.1
51.6
N.A.
76.1
N.A.
58.1
58.4
38.6
60
Protein Similarity:
100
71.8
99.7
98.8
N.A.
97.9
97.3
N.A.
54.2
57.5
N.A.
85.8
N.A.
72.2
75.5
57.2
75.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
6.6
N.A.
0
N.A.
66.6
13.3
13.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
6.6
N.A.
13.3
N.A.
80
20
13.3
93.3
Percent
Protein Identity:
49.2
N.A.
N.A.
48
41.8
N.A.
Protein Similarity:
63.4
N.A.
N.A.
64.7
59.8
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
19
0
0
7
0
0
0
0
0
0
0
0
7
7
% A
% Cys:
0
0
44
7
7
0
13
0
7
13
0
0
0
7
0
% C
% Asp:
7
0
7
7
50
57
7
0
7
7
7
19
7
7
7
% D
% Glu:
7
13
7
13
0
7
0
0
0
0
13
7
0
7
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
13
7
7
0
0
0
7
7
0
7
7
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
7
7
0
% H
% Ile:
7
7
0
0
0
0
0
0
7
0
50
7
0
0
13
% I
% Lys:
0
7
0
0
7
0
7
0
0
13
7
0
0
7
0
% K
% Leu:
0
0
0
7
0
7
0
0
7
0
7
0
7
7
7
% L
% Met:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
0
0
0
0
7
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
7
0
0
0
0
7
44
0
% Q
% Arg:
7
7
7
0
7
7
44
7
0
38
7
0
44
0
0
% R
% Ser:
0
50
7
50
7
7
0
7
7
7
13
0
13
0
0
% S
% Thr:
7
0
13
0
0
0
7
63
13
0
0
7
0
7
13
% T
% Val:
7
0
0
0
0
7
13
13
50
13
0
0
7
7
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
50
7
0
0
% W
% Tyr:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _