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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIAO1
All Species:
28.18
Human Site:
T291
Identified Species:
41.33
UniProt:
O76071
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76071
NP_004795.1
339
37840
T291
N
S
D
P
Q
Q
P
T
F
S
L
T
A
H
L
Chimpanzee
Pan troglodytes
XP_001144741
472
51924
T424
N
S
D
P
Q
Q
P
T
F
S
L
T
A
H
L
Rhesus Macaque
Macaca mulatta
XP_001098395
339
37880
T291
N
S
D
P
Q
Q
P
T
F
S
L
T
A
H
L
Dog
Lupus familis
XP_532950
339
37846
T291
S
S
D
P
Q
Q
P
T
F
S
L
T
A
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99KN2
339
37614
T291
G
S
D
P
Q
Q
P
T
F
S
L
T
A
H
L
Rat
Rattus norvegicus
Q5M7T1
339
37599
T291
G
S
D
P
Q
Q
P
T
F
S
L
T
A
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517379
223
24600
R179
L
A
T
C
S
D
D
R
T
V
R
I
W
R
Q
Chicken
Gallus gallus
XP_423992
209
23301
T165
Q
Q
P
T
F
S
L
T
A
H
V
P
R
A
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0D9
330
36784
F286
A
D
P
E
Q
P
I
F
A
L
S
A
H
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K1Y4
335
37026
T291
D
S
K
P
D
E
P
T
F
E
Q
I
T
A
E
Honey Bee
Apis mellifera
XP_395314
332
37365
Q288
D
S
D
S
D
P
H
Q
P
T
F
T
M
V
C
Nematode Worm
Caenorhab. elegans
Q9XW12
337
38172
P291
I
S
S
T
P
E
S
P
V
I
E
H
L
G
V
Sea Urchin
Strong. purpuratus
XP_781960
340
38037
T293
Q
D
R
R
N
Q
P
T
F
D
L
A
V
K
T
Poplar Tree
Populus trichocarpa
XP_002299788
323
35737
D279
E
S
K
D
G
L
V
D
G
P
S
Y
K
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565615
352
39113
S305
H
D
S
V
D
G
P
S
Y
N
L
L
L
K
K
Baker's Yeast
Sacchar. cerevisiae
Q05583
330
37256
F286
V
D
G
E
W
K
V
F
A
K
R
A
L
C
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
99.7
97.3
N.A.
94.9
94.4
N.A.
50.1
51.6
N.A.
76.1
N.A.
58.1
58.4
38.6
60
Protein Similarity:
100
71.8
99.7
98.8
N.A.
97.9
97.3
N.A.
54.2
57.5
N.A.
85.8
N.A.
72.2
75.5
57.2
75.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
6.6
N.A.
6.6
N.A.
33.3
20
6.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
6.6
13.3
N.A.
6.6
N.A.
46.6
33.3
20
33.3
Percent
Protein Identity:
49.2
N.A.
N.A.
48
41.8
N.A.
Protein Similarity:
63.4
N.A.
N.A.
64.7
59.8
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
40
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
0
19
0
0
19
38
13
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
7
% C
% Asp:
13
25
44
7
19
7
7
7
0
7
0
0
0
0
0
% D
% Glu:
7
0
0
13
0
13
0
0
0
7
7
0
0
0
7
% E
% Phe:
0
0
0
0
7
0
0
13
50
0
7
0
0
0
0
% F
% Gly:
13
0
7
0
7
7
0
0
7
0
0
0
0
7
0
% G
% His:
7
0
0
0
0
0
7
0
0
7
0
7
7
38
13
% H
% Ile:
7
0
0
0
0
0
7
0
0
7
0
13
0
0
0
% I
% Lys:
0
0
13
0
0
7
0
0
0
7
0
0
7
13
7
% K
% Leu:
7
0
0
0
0
7
7
0
0
7
50
7
19
7
44
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
19
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
13
44
7
13
57
7
7
7
0
7
0
0
7
% P
% Gln:
13
7
0
0
44
44
0
7
0
0
7
0
0
0
7
% Q
% Arg:
0
0
7
7
0
0
0
7
0
0
13
0
7
7
0
% R
% Ser:
7
63
13
7
7
7
7
7
0
38
13
0
0
0
0
% S
% Thr:
0
0
7
13
0
0
0
57
7
7
0
44
7
0
7
% T
% Val:
7
0
0
7
0
0
13
0
7
7
7
0
7
13
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _