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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIAO1
All Species:
30.61
Human Site:
T63
Identified Species:
44.89
UniProt:
O76071
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76071
NP_004795.1
339
37840
T63
L
S
E
G
H
Q
R
T
V
R
K
V
A
W
S
Chimpanzee
Pan troglodytes
XP_001144741
472
51924
T196
L
S
E
G
H
Q
R
T
V
R
K
V
A
W
S
Rhesus Macaque
Macaca mulatta
XP_001098395
339
37880
T63
L
S
E
G
H
Q
R
T
V
R
K
V
A
W
S
Dog
Lupus familis
XP_532950
339
37846
T63
L
S
E
G
H
Q
R
T
V
R
K
V
A
W
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99KN2
339
37614
T63
L
S
E
G
H
Q
R
T
V
R
K
V
A
W
S
Rat
Rattus norvegicus
Q5M7T1
339
37599
T63
L
S
E
G
H
Q
R
T
V
R
K
V
A
W
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517379
223
24600
Chicken
Gallus gallus
XP_423992
209
23301
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0D9
330
36784
G59
C
K
C
V
L
S
D
G
H
Q
R
T
V
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K1Y4
335
37026
R63
D
G
H
K
R
T
I
R
E
I
R
W
S
P
C
Honey Bee
Apis mellifera
XP_395314
332
37365
T61
L
I
E
G
H
T
R
T
I
R
E
V
A
W
S
Nematode Worm
Caenorhab. elegans
Q9XW12
337
38172
D64
E
C
R
T
T
L
D
D
S
H
T
R
A
V
R
Sea Urchin
Strong. purpuratus
XP_781960
340
38037
V63
Q
D
G
H
T
R
T
V
R
R
V
A
W
S
P
Poplar Tree
Populus trichocarpa
XP_002299788
323
35737
T52
A
V
L
E
E
T
H
T
R
T
V
R
S
C
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565615
352
39113
T76
L
E
E
T
H
T
R
T
V
R
S
C
A
W
S
Baker's Yeast
Sacchar. cerevisiae
Q05583
330
37256
K59
L
D
E
T
A
H
K
K
A
I
R
S
V
A
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
99.7
97.3
N.A.
94.9
94.4
N.A.
50.1
51.6
N.A.
76.1
N.A.
58.1
58.4
38.6
60
Protein Similarity:
100
71.8
99.7
98.8
N.A.
97.9
97.3
N.A.
54.2
57.5
N.A.
85.8
N.A.
72.2
75.5
57.2
75.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
0
N.A.
0
N.A.
0
73.3
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
0
N.A.
13.3
N.A.
13.3
86.6
6.6
13.3
Percent
Protein Identity:
49.2
N.A.
N.A.
48
41.8
N.A.
Protein Similarity:
63.4
N.A.
N.A.
64.7
59.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
66.6
13.3
N.A.
P-Site Similarity:
20
N.A.
N.A.
66.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
0
0
7
0
0
7
57
7
7
% A
% Cys:
7
7
7
0
0
0
0
0
0
0
0
7
0
7
7
% C
% Asp:
7
13
0
0
0
0
13
7
0
0
0
0
0
0
0
% D
% Glu:
7
7
57
7
7
0
0
0
7
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
44
0
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
7
7
50
7
7
0
7
7
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
7
0
7
13
0
0
0
0
0
% I
% Lys:
0
7
0
7
0
0
7
7
0
0
38
0
0
0
7
% K
% Leu:
57
0
7
0
7
7
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% P
% Gln:
7
0
0
0
0
38
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
7
0
7
7
50
7
13
57
19
13
0
7
7
% R
% Ser:
0
38
0
0
0
7
0
0
7
0
7
7
13
7
50
% S
% Thr:
0
0
0
19
13
25
7
57
0
7
7
7
0
0
0
% T
% Val:
0
7
0
7
0
0
0
7
44
0
13
44
13
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
7
50
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _