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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DFFB
All Species:
19.09
Human Site:
S83
Identified Species:
52.5
UniProt:
O76075
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76075
NP_004393.1
338
39110
S83
Q
A
W
Q
G
Y
V
S
D
I
R
R
F
L
S
Chimpanzee
Pan troglodytes
XP_001153262
339
38739
S83
Q
A
W
Q
G
Y
V
S
D
I
G
R
F
L
S
Rhesus Macaque
Macaca mulatta
XP_001087149
322
36092
S83
Q
A
W
Q
G
Y
V
S
D
I
G
R
F
L
S
Dog
Lupus familis
XP_546743
341
38911
S86
Q
T
W
Q
G
Y
V
S
D
I
S
G
F
L
S
Cat
Felis silvestris
Mouse
Mus musculus
O54788
344
39431
S86
E
T
W
H
G
Y
V
S
D
I
T
R
F
L
S
Rat
Rattus norvegicus
Q99N34
349
40078
S86
E
T
W
H
G
Y
V
S
D
I
T
R
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515733
188
21855
Chicken
Gallus gallus
NP_989616
333
38455
G83
E
S
W
P
G
C
C
G
D
V
E
R
F
L
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_919385
333
38322
D85
Q
S
W
N
G
F
A
D
E
I
N
R
V
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
56.5
77.7
N.A.
76.4
75
N.A.
40.5
58.8
N.A.
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.8
61.8
86.2
N.A.
86.6
85
N.A.
49.4
74.2
N.A.
71
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
80
N.A.
73.3
66.6
N.A.
0
40
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
80
N.A.
80
73.3
N.A.
0
66.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
0
0
12
0
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
78
0
0
0
0
0
0
% D
% Glu:
34
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
67
0
0
% F
% Gly:
0
0
0
0
89
0
0
12
0
0
23
12
0
0
12
% G
% His:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
78
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
12
89
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
56
0
0
45
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
12
78
0
0
0
% R
% Ser:
0
23
0
0
0
0
0
67
0
0
12
0
0
0
67
% S
% Thr:
0
34
0
0
0
0
0
0
0
0
23
0
0
0
0
% T
% Val:
0
0
0
0
0
0
67
0
0
12
0
0
12
0
0
% V
% Trp:
0
0
89
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _