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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A5
All Species:
28.79
Human Site:
S466
Identified Species:
57.58
UniProt:
O76082
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76082
NP_003051.1
557
62752
S466
R
N
M
G
V
G
V
S
S
T
A
S
R
L
G
Chimpanzee
Pan troglodytes
XP_001163062
551
62237
V461
T
L
V
R
N
M
A
V
G
V
T
S
T
A
S
Rhesus Macaque
Macaca mulatta
XP_001103789
557
62650
S466
R
N
M
G
V
G
V
S
S
T
A
S
R
L
G
Dog
Lupus familis
XP_860734
557
62646
S466
R
N
M
G
V
G
V
S
S
T
A
S
R
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0E8
557
62761
S466
R
N
M
G
V
G
V
S
S
T
A
S
R
L
G
Rat
Rattus norvegicus
O70594
557
62549
S466
R
N
M
G
V
G
V
S
S
T
A
S
R
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510318
557
62019
S466
R
N
M
G
V
G
A
S
S
M
A
S
R
F
G
Chicken
Gallus gallus
NP_001039293
557
62686
S466
R
N
M
G
V
G
A
S
S
M
A
S
R
L
G
Frog
Xenopus laevis
Q66KG0
566
63736
G473
R
S
L
A
V
G
S
G
S
M
M
C
R
I
G
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
V469
R
Q
S
G
M
G
W
V
S
M
M
A
R
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
G456
P
T
V
V
R
N
V
G
L
G
A
S
S
M
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U539
585
65444
S482
R
A
I
G
M
G
M
S
S
M
V
A
G
S
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.1
98.1
90.3
N.A.
85.4
85.4
N.A.
72.1
75.7
31.9
31.9
N.A.
35.5
N.A.
29
N.A.
Protein Similarity:
100
86.7
99.6
95.8
N.A.
92.4
93
N.A.
84.5
86.5
54.9
50.1
N.A.
56
N.A.
49
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
80
86.6
40
40
N.A.
20
N.A.
40
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
80
86.6
60
53.3
N.A.
33.3
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
25
0
0
0
67
17
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% F
% Gly:
0
0
0
75
0
84
0
17
9
9
0
0
9
0
84
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
9
0
0
0
0
0
9
0
0
0
0
50
0
% L
% Met:
0
0
59
0
17
9
9
0
0
42
17
0
0
9
0
% M
% Asn:
0
59
0
0
9
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
84
0
0
9
9
0
0
0
0
0
0
0
75
0
0
% R
% Ser:
0
9
9
0
0
0
9
67
84
0
0
75
9
9
9
% S
% Thr:
9
9
0
0
0
0
0
0
0
42
9
0
9
0
0
% T
% Val:
0
0
17
9
67
0
50
17
0
9
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _