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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE9A
All Species:
12.42
Human Site:
T567
Identified Species:
22.78
UniProt:
O76083
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76083
NP_001001567.1
593
68493
T567
M
K
E
L
Q
K
K
T
D
S
L
T
S
G
A
Chimpanzee
Pan troglodytes
XP_001140174
593
68430
T567
M
K
E
L
Q
K
K
T
D
S
L
T
S
G
A
Rhesus Macaque
Macaca mulatta
NP_001154921
533
61639
T507
M
K
E
L
Q
K
K
T
D
S
L
T
S
G
A
Dog
Lupus familis
XP_853727
850
94841
A621
V
W
G
R
R
R
L
A
Q
T
Q
S
G
S
A
Cat
Felis silvestris
Mouse
Mus musculus
O70628
534
61617
L509
L
Q
K
K
T
E
S
L
T
S
G
A
P
E
N
Rat
Rattus norvegicus
P14270
803
90534
S747
E
S
D
T
E
K
D
S
G
S
Q
V
E
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511668
533
61943
Q507
M
K
E
L
Q
Q
Q
Q
E
D
V
T
S
G
N
Chicken
Gallus gallus
XP_416748
516
59987
Y490
L
W
E
S
R
D
R
Y
E
E
L
K
Q
I
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001340244
516
59766
L491
S
R
D
K
Y
E
E
L
K
Q
I
D
D
A
M
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
V874
Q
H
D
H
G
A
S
V
P
A
S
P
C
S
A
Fruit Fly
Dros. melanogaster
P12252
1070
115060
E997
G
V
D
E
N
P
Q
E
D
R
I
R
F
Q
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22000
674
75370
N649
I
L
D
Q
L
E
E
N
R
E
W
Y
Q
S
R
Sea Urchin
Strong. purpuratus
XP_794310
409
47790
Q384
A
L
Y
R
Y
E
E
Q
K
L
K
E
D
Q
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
88.8
58.5
N.A.
83.1
24
N.A.
73.8
76.7
N.A.
67.6
21.1
20.1
N.A.
25.8
44.8
Protein Similarity:
100
99.4
89.3
61.4
N.A.
87.1
41.2
N.A.
80.2
82.4
N.A.
79.7
36.5
34.6
N.A.
44
56.8
P-Site Identity:
100
100
100
6.6
N.A.
6.6
13.3
N.A.
53.3
13.3
N.A.
0
6.6
6.6
N.A.
0
0
P-Site Similarity:
100
100
100
40
N.A.
33.3
33.3
N.A.
80
40
N.A.
33.3
20
26.6
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
8
0
8
0
8
0
8
39
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
39
0
0
8
8
0
31
8
0
8
16
0
16
% D
% Glu:
8
0
39
8
8
31
24
8
16
16
0
8
8
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
8
0
8
0
0
0
8
0
8
0
8
31
0
% G
% His:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
16
0
0
8
8
% I
% Lys:
0
31
8
16
0
31
24
0
16
0
8
8
0
0
0
% K
% Leu:
16
16
0
31
8
0
8
16
0
8
31
0
0
0
0
% L
% Met:
31
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
16
% N
% Pro:
0
0
0
0
0
8
0
0
8
0
0
8
8
0
0
% P
% Gln:
8
8
0
8
31
8
16
16
8
8
16
0
16
16
0
% Q
% Arg:
0
8
0
16
16
8
8
0
8
8
0
8
0
0
8
% R
% Ser:
8
8
0
8
0
0
16
8
0
39
8
8
31
24
0
% S
% Thr:
0
0
0
8
8
0
0
24
8
8
0
31
0
0
0
% T
% Val:
8
8
0
0
0
0
0
8
0
0
8
8
0
0
8
% V
% Trp:
0
16
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
8
0
16
0
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _