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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BEST1 All Species: 31.82
Human Site: T348 Identified Species: 70
UniProt: O76090 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76090 NP_001132915.1 585 67684 T348 P E P Q P P Y T A A S A Q F R
Chimpanzee Pan troglodytes XP_522029 664 76228 T348 P E P Q P P Y T A A S A Q F R
Rhesus Macaque Macaca mulatta XP_001116583 585 67469 T348 P E P H P P Y T A A S A Q F R
Dog Lupus familis XP_538279 765 85787 T443 S A A R P P Y T L A A A D Y C
Cat Felis silvestris
Mouse Mus musculus O88870 551 63638 T348 A A P Q P P Y T A A S A R S R
Rat Rattus norvegicus NP_001011940 550 63922 T348 A A P Q P P Y T A A S A G S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512039 818 92939 T348 S A A Q P P Y T L A A A D Y C
Chicken Gallus gallus XP_421055 762 85767 T348 P D P Q P P Y T A A T A E Y K
Frog Xenopus laevis NP_001080317 512 59003 F315 N F L I D R N F Q V S M L A V
Zebra Danio Brachydanio rerio XP_689098 717 80953 T348 A E P Q P P Y T A A S A E H R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34672 632 73810 S347 E E V E P L Y S E E T A K I P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.6 96.5 38.9 N.A. 64.4 62.2 N.A. 39.8 48.5 48 45.3 N.A. N.A. N.A. 29.1 N.A.
Protein Similarity: 100 87.8 97.2 50 N.A. 74.8 75.2 N.A. 51.2 61.4 62.7 58.4 N.A. N.A. N.A. 48.8 N.A.
P-Site Identity: 100 100 93.3 40 N.A. 73.3 66.6 N.A. 46.6 66.6 6.6 80 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 100 100 93.3 60 N.A. 80 66.6 N.A. 60 100 6.6 86.6 N.A. N.A. N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 37 19 0 0 0 0 0 64 82 19 91 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % C
% Asp: 0 10 0 0 10 0 0 0 0 0 0 0 19 0 0 % D
% Glu: 10 46 0 10 0 0 0 0 10 10 0 0 19 0 0 % E
% Phe: 0 10 0 0 0 0 0 10 0 0 0 0 0 28 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 10 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % K
% Leu: 0 0 10 0 0 10 0 0 19 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 37 0 64 0 91 82 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 64 0 0 0 0 10 0 0 0 28 0 0 % Q
% Arg: 0 0 0 10 0 10 0 0 0 0 0 0 10 0 46 % R
% Ser: 19 0 0 0 0 0 0 10 0 0 64 0 0 19 0 % S
% Thr: 0 0 0 0 0 0 0 82 0 0 19 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 91 0 0 0 0 0 0 28 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _