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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BEST1
All Species:
10
Human Site:
Y464
Identified Species:
22
UniProt:
O76090
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76090
NP_001132915.1
585
67684
Y464
P
L
Y
Q
R
P
G
Y
Y
S
A
P
Q
T
P
Chimpanzee
Pan troglodytes
XP_522029
664
76228
Y464
P
L
Y
Q
R
P
G
Y
Y
S
A
P
Q
T
P
Rhesus Macaque
Macaca mulatta
XP_001116583
585
67469
Y464
P
L
Y
Q
R
P
G
Y
Y
S
A
P
Q
T
P
Dog
Lupus familis
XP_538279
765
85787
P543
P
T
G
P
R
R
A
P
G
A
R
Q
P
C
S
Cat
Felis silvestris
Mouse
Mus musculus
O88870
551
63638
Q427
K
N
P
L
L
E
G
Q
C
K
D
A
N
Q
K
Rat
Rattus norvegicus
NP_001011940
550
63922
Q431
D
Q
S
K
N
D
K
Q
K
D
Q
K
N
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512039
818
92939
F627
K
R
W
S
L
P
E
F
L
E
S
S
Q
T
T
Chicken
Gallus gallus
XP_421055
762
85767
F479
P
F
Y
E
R
P
G
F
Y
S
A
P
Q
T
P
Frog
Xenopus laevis
NP_001080317
512
59003
L394
E
D
T
L
M
H
P
L
P
L
L
S
R
F
L
Zebra Danio
Brachydanio rerio
XP_689098
717
80953
F468
P
L
Y
E
R
P
G
F
Y
S
C
P
Q
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34672
632
73810
S478
G
S
H
A
N
N
N
S
F
T
N
S
A
F
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.6
96.5
38.9
N.A.
64.4
62.2
N.A.
39.8
48.5
48
45.3
N.A.
N.A.
N.A.
29.1
N.A.
Protein Similarity:
100
87.8
97.2
50
N.A.
74.8
75.2
N.A.
51.2
61.4
62.7
58.4
N.A.
N.A.
N.A.
48.8
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
6.6
0
N.A.
20
80
0
80
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
20
N.A.
6.6
6.6
N.A.
40
93.3
6.6
93.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
0
0
10
37
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% C
% Asp:
10
10
0
0
0
10
0
0
0
10
10
0
0
10
0
% D
% Glu:
10
0
0
19
0
10
10
0
0
10
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
28
10
0
0
0
0
19
0
% F
% Gly:
10
0
10
0
0
0
55
0
10
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
0
0
10
0
0
10
0
10
10
0
10
0
0
10
% K
% Leu:
0
37
0
19
19
0
0
10
10
10
10
0
0
0
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
19
10
10
0
0
0
10
0
19
0
0
% N
% Pro:
55
0
10
10
0
55
10
10
10
0
0
46
10
0
46
% P
% Gln:
0
10
0
28
0
0
0
19
0
0
10
10
55
10
0
% Q
% Arg:
0
10
0
0
55
10
0
0
0
0
10
0
10
0
0
% R
% Ser:
0
10
10
10
0
0
0
10
0
46
10
28
0
0
10
% S
% Thr:
0
10
10
0
0
0
0
0
0
10
0
0
0
55
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
46
0
0
0
0
28
46
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _